成功治疗 17 岁少女严重钙通道阻滞剂中毒：一项新的有创血流动力学监测指导下的病例报告。
Successful treatment of severe calcium channel blocker poisoning, new experience with the guidance of invasive hemodynamic monitoring in a 17-year-old girl: a case report.
机构信息
Scientific Association of Intensive Care and ICU of Iran, Tehran, Iran.
Cardiovascular and Neonatology Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
J Med Case Rep. 2024 Feb 3;18(1):68. doi: 10.1186/s13256-024-04345-1.
BACKGROUND
Calcium channel blocker poisoning is one of the most lethal cardiac drugs overdoses. Calcium and high-dose insulin infusion are the first-line therapy for symptomatic patients, and Intralipid emulsion infusion is useful for refractory cases.
CASE PRESENTATION
In this report, we describe a 17-year-old Iranian girl who took 250 mg of the drug for a suicidal attempt and presented with refractory hypotension and non-cardiogenic pulmonary edema treated successfully with the guidance of invasive hemodynamic parameters.
CONCLUSION
For complicated cases, in addition to supportive care and adjuvant therapy such as high-dose insulin and Intralipid, it is mandatory to utilize advanced hemodynamic monitoring to treat hypotension in severe calcium channel blocker poisoning to guide the treatment.
背景
钙通道阻滞剂中毒是最致命的心脏药物中毒之一。钙和高剂量胰岛素输注是有症状患者的一线治疗方法，而脂肪乳剂输注对难治性病例有用。
病例介绍
在本报告中，我们描述了一位 17 岁的伊朗女孩，她因自杀企图而服用了 250 毫克该药物，出现难治性低血压和非心源性肺水肿，在侵入性血流动力学参数的指导下成功治疗。
结论
对于复杂病例，除了支持性护理和辅助治疗，如大剂量胰岛素和脂肪乳剂，还必须利用先进的血流动力学监测来治疗严重钙通道阻滞剂中毒中的低血压，以指导治疗。
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