Desmoplasia Is Associated with Decreased Cytotoxic and Helper T Cells and Increased T-Cell Exhaustion in Cutaneous Squamous Cell Carcinoma.
作者信息
Hirakawa Yuka, Zhan Qian, Essien Sernah, Yu Kenneth K, Murad Fadi, Piris Adriano, Ramsey Matthew R, Schatton Tobias, Carucci John A, Schmults Chrysalyne D
机构信息
Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
出版信息
J Invest Dermatol. 2024 Aug;144(8):1901-1904.e2. doi: 10.1016/j.jid.2024.01.019. Epub 2024 Feb 2.
Abstract
摘要
相似文献
1
Desmoplasia Is Associated with Decreased Cytotoxic and Helper T Cells and Increased T-Cell Exhaustion in Cutaneous Squamous Cell Carcinoma.促纤维增生与皮肤鳞状细胞癌中细胞毒性T细胞和辅助性T细胞减少以及T细胞耗竭增加有关。
J Invest Dermatol. 2024 Aug;144(8):1901-1904.e2. doi: 10.1016/j.jid.2024.01.019. Epub 2024 Feb 2.
2
Pretreatment nutritional indices are associated with survival and T-cell exhaustion in recurrent or metastatic oral squamous cell carcinoma patients treated with immune checkpoint inhibitors: a retrospective cohort study.预处理营养指标与接受免疫检查点抑制剂治疗的复发性或转移性口腔鳞状细胞癌患者的生存率及T细胞耗竭相关：一项回顾性队列研究
Int J Oral Maxillofac Surg. 2025 Aug;54(8):685-694. doi: 10.1016/j.ijom.2025.01.010. Epub 2025 Feb 11.
3
Immunohistochemical study of mononuclear cell infiltrates in squamous cell carcinoma of oral cavity and paranasal sinus.口腔及鼻窦鳞状细胞癌中单核细胞浸润的免疫组织化学研究
Oncology. 1987;44(4):219-23. doi: 10.1159/000226481.
4
OX40+ Regulatory T Cells in Cutaneous Squamous Cell Carcinoma Suppress Effector T-Cell Responses and Associate with Metastatic Potential.皮肤鳞状细胞癌中的OX40+调节性T细胞抑制效应T细胞反应并与转移潜能相关。
Clin Cancer Res. 2016 Aug 15;22(16):4236-48. doi: 10.1158/1078-0432.CCR-15-2614. Epub 2016 Mar 31.
5
[Changes of peripheral lymphocyte subsets in patients with oral squamous carcinoma].[口腔鳞状细胞癌患者外周血淋巴细胞亚群的变化]
Gan No Rinsho. 1985 Feb;31(2):117-21.
6
[T follicular helper cell lesions and mimics in dermatopathology: From theory to practice].[皮肤病理学中的T滤泡辅助细胞病变及类似病变：从理论到实践]
Ann Pathol. 2025 Jul;45(4):334-348. doi: 10.1016/j.annpat.2025.04.002. Epub 2025 May 6.
7
Spatial Profiles of Intratumoral PD-1 Helper T Cells Predict Prognosis in Head and Neck Squamous Cell Carcinoma.肿瘤内 PD-1 辅助性 T 细胞的空间分布预测头颈部鳞状细胞癌的预后。
Front Immunol. 2021 Oct 28;12:769534. doi: 10.3389/fimmu.2021.769534. eCollection 2021.
8
Evaluation of T-lymphocyte subpopulations in actinic keratosis, in situ and invasive squamous cell carcinoma of the skin.光化性角化病、皮肤原位鳞状细胞癌及浸润性鳞状细胞癌中T淋巴细胞亚群的评估。
J Cutan Pathol. 2018 May;45(5):337-347. doi: 10.1111/cup.13123. Epub 2018 Mar 14.
9
Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma.Ce6衍生物光动力疗法在皮肤鳞状细胞癌中通过阻断LAG3触发PAN细胞焦亡并增强抗肿瘤免疫力。
Cell Rep Med. 2025 Jul 15;6(7):102239. doi: 10.1016/j.xcrm.2025.102239.
10
CD73 Is an Immunometabolic Biomarker of Poor Prognosis in Patients With Primary Cutaneous Squamous Cell Carcinoma and Hematologic Malignancy.CD73 是原发性皮肤鳞状细胞癌和血液系统恶性肿瘤患者预后不良的免疫代谢生物标志物。
Dermatol Surg. 2024 Dec 1;50(12):1096-1101. doi: 10.1097/DSS.0000000000004310. Epub 2024 Jul 8.
本文引用的文献
1
Prognostic Impact of Perineural Invasion in Cutaneous Squamous Cell Carcinoma: Results of a Prospective Study of 1,399 Tumors.皮肤鳞状细胞癌中神经周围侵犯的预后影响：一项对 1399 例肿瘤的前瞻性研究结果。
J Invest Dermatol. 2020 Oct;140(10):1968-1975. doi: 10.1016/j.jid.2020.01.035. Epub 2020 Mar 10.
2
Incidence and mortality for cutaneous squamous cell carcinoma: comparison across three continents.皮肤鳞状细胞癌的发病率和死亡率：三大洲的比较。
J Eur Acad Dermatol Venereol. 2019 Dec;33 Suppl 8(Suppl 8):6-10. doi: 10.1111/jdv.15967.
3
Composition and Clinical Impact of the Immunologic Tumor Microenvironment in Oral Squamous Cell Carcinoma.口腔鳞状细胞癌中免疫肿瘤微环境的组成与临床影响。
J Immunol. 2019 Jan 1;202(1):278-291. doi: 10.4049/jimmunol.1800242. Epub 2018 Dec 10.
4
PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma.西妥昔单抗联合 PD-1 抑制剂治疗晚期皮肤鳞状细胞癌的疗效和安全性
N Engl J Med. 2018 Jul 26;379(4):341-351. doi: 10.1056/NEJMoa1805131. Epub 2018 Jun 4.
5
The Prognostic Significance of the Tumor-infiltrating Programmed Cell Death-1 to CD8 Lymphocyte Ratio in Patients with Colorectal Cancer.肿瘤浸润程序性细胞死亡蛋白1与CD8淋巴细胞比值在结直肠癌患者中的预后意义
Anticancer Res. 2017 Aug;37(8):4165-4172. doi: 10.21873/anticanres.11804.
6
Survival of Patients with Cutaneous Squamous Cell Carcinoma: Results of a Prospective Cohort Study.皮肤鳞状细胞癌患者的生存情况：一项前瞻性队列研究的结果
J Invest Dermatol. 2017 Nov;137(11):2309-2315. doi: 10.1016/j.jid.2017.06.025. Epub 2017 Jul 21.
7
Tim-3 and its role in regulating anti-tumor immunity.Tim-3及其在调节抗肿瘤免疫中的作用。
Immunol Rev. 2017 Mar;276(1):97-111. doi: 10.1111/imr.12520.
8
The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltration.胰腺癌的促结缔组织增生性基质是免疫细胞浸润的障碍。
Oncoimmunology. 2013 Dec 1;2(12):e26788. doi: 10.4161/onci.26788. Epub 2013 Oct 22.
9
Evaluation of American Joint Committee on Cancer, International Union Against Cancer, and Brigham and Women's Hospital tumor staging for cutaneous squamous cell carcinoma.评估美国癌症联合委员会、国际抗癌联盟和布莱根妇女医院的皮肤鳞状细胞癌肿瘤分期系统。
J Clin Oncol. 2014 Feb 1;32(4):327-34. doi: 10.1200/JCO.2012.48.5326. Epub 2013 Dec 23.
10
Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients.Tim-3 和 PD-1 表达的上调与黑色素瘤患者肿瘤抗原特异性 CD8+ T 细胞功能障碍有关。
J Exp Med. 2010 Sep 27;207(10):2175-86. doi: 10.1084/jem.20100637. Epub 2010 Sep 6.
Zotero 插件