Kaselas Christos, Florou Maria, Tirta Maria, Bitzika Sophia, Sidiropoulou Daphne, Spyridakis Ioannis
2nd Department of Pediatric Surgery, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, GRC.
School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Cureus. 2024 Jan 3;16(1):e51580. doi: 10.7759/cureus.51580. eCollection 2024 Jan.
Congenital cryptorchidism or undescended testes (UDT) is one of the most common congenital abnormalities in newborns. Current guidelines recommend that surgical management should be scheduled by the 12th month and no later than the 18th month of the child's life. This is the first study to evaluate the age of diagnosis and surgical treatment of children with UDT in Greece, as well as the compliance with current guidelines worldwide.
A retrospective analysis of patients with UDT who underwent orchidopexy from 2015 to 2019 was conducted. Patient age at diagnosis and orchidopexy and the meantime between were recorded. Patients were separated into groups, based on the diagnosis age: group A, diagnosis until the 11th month; group B, diagnosis between the 12th and 18th month; and group C, diagnosis at >18th month.
We identified 217 children who were diagnosed with UDT and underwent orchidopexy in our department. The majority of the patients (47.4%) had right-sided UDT, while 25.3% of them had UDT on both sides. There were 89 (41%) children in group A, 20 (9.2%) in group B, and 108 (49.8%) males in group C. The median age at diagnosis was 18 months (range: 1-164 months), while for groups A, B, and C, the median age at diagnosis was five, 15, and 71.5 months, respectively. The median age at orchidopexy was 23 months (range: 6-166 months), and for each aforementioned group, it was 11, 16.5, and 74 months. The median waiting time for the orchidopexy was 84 days (range: 1-692 days), and for each group, it was 157, 42, and 56 days, respectively. The delay between diagnosis and surgery was significantly greater for group A compared to groups B and C (p = 0.01 and p < 0.0001), while there was no difference in the delay between groups B and C (p > 0.05).
Patient age at diagnosis and applied orchidopexy was within the recommended range for almost half of the patients. The rest of them had delayed diagnosis and surgery due to delayed referral. In delayed cases, the time from diagnosis to treatment was significantly shorter. Early surgical referral leading to prompt treatment will increase compliance with the guidelines and improve the quality and the outcomes of the provided health-care services.
先天性隐睾症或睾丸未降(UDT)是新生儿中最常见的先天性异常之一。当前指南建议手术治疗应在患儿12个月时安排,最迟不超过18个月。这是第一项评估希腊UDT患儿诊断和手术治疗年龄以及全球范围内对现行指南依从性的研究。
对2015年至2019年接受睾丸固定术的UDT患者进行回顾性分析。记录诊断时和睾丸固定术时的患者年龄以及两者之间的时间间隔。根据诊断年龄将患者分为几组:A组,诊断至11个月;B组,诊断在12至18个月之间;C组,诊断在18个月之后。
我们确定了217名在我科被诊断为UDT并接受睾丸固定术的儿童。大多数患者(47.4%)为右侧UDT,而25.3%为双侧UDT。A组有89名(41%)儿童,B组有20名(9.2%),C组有108名(49.8%)男性。诊断时的中位年龄为18个月(范围:1 - 164个月),而A、B、C组诊断时的中位年龄分别为5、15和71.5个月。睾丸固定术时的中位年龄为23个月(范围:6 - 166个月),上述每组分别为11、16.5和74个月。睾丸固定术的中位等待时间为84天(范围:1 - 692天),每组分别为157、42和56天。与B组和C组相比,A组诊断与手术之间的延迟明显更大(p = 0.01,p < 0.0001),而B组和C组之间的延迟没有差异(p > 0.05)。
几乎一半患者的诊断年龄和实施睾丸固定术的年龄在推荐范围内。其余患者因转诊延迟而诊断和手术延迟。在延迟病例中,从诊断到治疗的时间明显更短。早期手术转诊以实现及时治疗将提高对指南的依从性,并改善所提供医疗服务的质量和结果。