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既对艾曲泊帕又对罗米司亭耐药的免疫性血小板减少症。

The problem of immune thrombocytopenia refractory to both eltrombopag and romiplostim.

机构信息

Division of Hematology Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Department of Hematology/Oncology, University Children's Hospital Basel, Basel, Switzerland.

出版信息

Br J Haematol. 2024 Apr;204(4):1143-1145. doi: 10.1111/bjh.19327. Epub 2024 Feb 6.

DOI:10.1111/bjh.19327
PMID:38319005
Abstract

Immune thrombocytopenia refractory to multiple thrombopoietin receptor agonists remains a challenging clinical problem. This commentary discusses and contextualizes the recent report on this entity from Moulis and colleagues, and how to move forward with these patients. Commentary on: Moulis et al. Difficult-to-treat primary immune thrombocytopenia in adults: Prevalence and burden. Results from the CARMEN-France Registry. Br J Haematol 2024;204:1476-1482.

摘要

对多种血小板生成素受体激动剂难治的免疫性血小板减少症仍然是一个具有挑战性的临床问题。本评论讨论并阐述了 Moulis 等人最近关于该疾病的报告,以及如何处理这些患者。评论:Moulis 等人。成人难治性原发性免疫性血小板减少症:患病率和负担。来自法国 CARMEN 登记处的结果。英国血液学杂志 2024;204:1476-1482。

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The problem of immune thrombocytopenia refractory to both eltrombopag and romiplostim.既对艾曲泊帕又对罗米司亭耐药的免疫性血小板减少症。
Br J Haematol. 2024 Apr;204(4):1143-1145. doi: 10.1111/bjh.19327. Epub 2024 Feb 6.
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Thrombopoietin Receptor Agonists: Eltrombopag and Romiplostim for the Treatment of Chronic Immune Thrombocytopenia Purpura.血小板生成素受体激动剂:艾曲泊帕和罗米司亭用于治疗慢性免疫性血小板减少性紫癜
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Safety and efficacy of romiplostim in patients with eltrombopag-resistant or -intolerant immune thrombocytopenia.罗米司亭在艾曲泊帕耐药或不耐受的免疫性血小板减少症患者中的安全性和有效性。
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Thrombopoietin receptor agonists in refractory immune thrombocytopenia: differential responses to eltrombopag and romiplostim: a case report and possible explanations.难治性免疫性血小板减少症中的血小板生成素受体激动剂:艾曲泊帕和罗米司亭的反应差异:一例病例报告及可能的解释。
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[Successful switching from eltrombopag to romiplostim in a pediatric patient with refractory chronic ITP].[一名难治性慢性免疫性血小板减少症儿科患者从艾曲泊帕成功转换为罗米司亭]
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Immune thrombocytopenia successfully treated with eltrombopag following multiple therapies including romiplostim.在接受包括罗米司亭在内的多种治疗后,艾曲泊帕成功治疗免疫性血小板减少症。
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Successful treatment of eltrombopag-resistant refractory immune thrombocytopenia with romiplostim.用罗米司亭成功治疗艾曲泊帕耐药的难治性免疫性血小板减少症。
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The use of thrombopoietin-receptor agonists (TPO-RAs) in immune thrombocytopenia (ITP): a "real life" retrospective multicenter experience of the Rete Ematologica Pugliese (REP).血小板生成素受体激动剂(TPO-RAs)在免疫性血小板减少症(ITP)中的应用:普利亚血液学网络(REP)的一项“真实生活”回顾性多中心经验。
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Relative potency of the thrombopoietin receptor agonists eltrombopag, avatrombopag and romiplostim in a patient with chronic immune thrombocytopenia.血小板生成素受体激动剂艾曲泊帕、阿伐曲泊帕和罗米司亭在一名慢性免疫性血小板减少症患者中的相对效价。
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