Girma Abayeneh, Tamir Dessalew
Department of Biology, College of Natural and Computational Sciences, Mekdela Amba University, P.O. Box 32, Tulu Awuliya, Ethiopia.
Department of Veterinary Science, College of Agriculture and Environmental Sciences, Debre Tabor University, Debre Tabor P.O. Box 272, Ethiopia.
J Equine Vet Sci. 2024 Mar;134:105012. doi: 10.1016/j.jevs.2024.105012. Epub 2024 Feb 4.
In Sub-Saharan Africa (SSA), particularly in Ethiopia, Epizootic Lymphangitis (EL) is the most prevalent fungal disease of equids, which causes significant economic losses as well as a decrease in equid populations. Therefore, this systematic review and meta-analysis were designed to pool the results of individual studies and estimate the prevalence of EL among equids in Ethiopia. A systematic search of research articles on the prevalence and risk factors of EL among equids in Ethiopia was conducted in registers, databases, and other sources. Cochrane's Q, inverse variance (I), sensitivity analysis, funnel plot, Begg's, and Egger's regression tests were used to check heterogeneity and publication bias. A random-effects model was used to calculate the pooled burden of EL among equids. For this meta-analysis, a total of 7217 equids were included in the 14 eligible studies. The overall pooled prevalence of EL among equids in Ethiopia was 20.24% (95% CI: 16.27, 24.21). According to the subgroup analysis, the highest prevalence was observed in cart horses (20.98%), the Amhara region (21.46%), and studies conducted using sample sizes of 384 equids or greater (24.67%) and from 2002 to 2018 (25.52%) study periods. Harness-inflicted wounds, sharing stables or yards with harnesses, and the presence of preexisting wounds were identified as factors significantly associated with EL magnitude. Early diagnosis and proper medication, as well as implementing appropriate prevention and control measures, are necessary for the management of EL in equids.
在撒哈拉以南非洲（SSA），特别是在埃塞俄比亚，流行性淋巴管炎（EL）是马属动物中最普遍的真菌疾病，它会造成重大经济损失，并导致马属动物数量减少。因此，本系统评价和荟萃分析旨在汇总个体研究结果，估计埃塞俄比亚马属动物中EL的患病率。我们在登记册、数据库和其他来源中对埃塞俄比亚马属动物中EL的患病率和危险因素的研究文章进行了系统检索。使用Cochrane's Q、逆方差（I）、敏感性分析、漏斗图、Begg检验和Egger回归检验来检查异质性和发表偏倚。采用随机效应模型计算马属动物中EL的合并负担。在这项荟萃分析中，14项符合条件的研究共纳入了7217匹马属动物。埃塞俄比亚马属动物中EL的总体合并患病率为20.24%（95%CI：16.27，24.21）。根据亚组分析，挽马（20.98%）、阿姆哈拉地区（21.46%）以及样本量为384匹或更多马属动物的研究（24.67%）和2002年至2018年的研究期间（25.52%）的患病率最高。发现挽具造成的伤口、与挽具共用马厩或场地以及存在既往伤口是与EL严重程度显著相关的因素。早期诊断和适当用药，以及实施适当的预防和控制措施，对于马属动物EL的管理是必要的。
