BACKGROUND: As information on the meniscus accumulates in PubMed, it is possible to evaluate the trends in research on the topic over time. PURPOSE: To evaluate the major trends in meniscus-related publications in PubMed from the earliest publication to the present day. STUDY DESIGN: Cross-sectional study. METHODS: PubMed was searched on January 3, 2023, using the search strategy "menisc *"[All Fields] AND ("knee"[MeSH Terms] OR "knee"[All Fields] OR "knee joint"[MeSH Terms] OR ("knee"[All Fields] AND "joint"[All Fields]) OR "knee joint"[All Fields]) AND 1900/01/01:2022/12/31[Date - Publication]. This retrieved 15,569 human and animal studies. We determined the top 10 meniscus-related publications in terms of overall citations and citations per year, as well as the top 10 authors, journals, countries, and institutions of cited publications on the meniscus. In addition, we performed word-cloud analyses based on meniscus-related terms from different periods (before 1981, before 2000, after 2005, and in the past 5 years [2018-2022]), including the year of first appearance and the number of publications featured. RESULTS: Since the first recorded publication on the meniscus in 1928, there was a steady growth in the number of articles until 2005, when there was an upsurge in publications from 254 in 2005 to 955 in 2022. Noyes was the author with the most citations (n = 3314), and a 2006 study by Caplan and Dennis had the most citations per year (n = 125). published the most articles on the meniscus with 1118, whereas the had the most citations per article with 125.69. The most published countries and institutes were the United States and the Hospital for Special Surgery, respectively. Word-cloud analysis of article titles showed that "meniscectomy" had become less prominent, and "root,""ramp,""transplantation," and "slope" had become more prominent. CONCLUSION: There has been an upsurge in publications on the meniscus since 2005, with word-cloud analysis indicating shifting interests in meniscus-related research.