Department of Ophthalmology, Ningbo Eye Hospital, Ningbo, China.
Department of Ophthalmology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Eur J Ophthalmol. 2024 Sep;34(5):1569-1575. doi: 10.1177/11206721241232029. Epub 2024 Feb 7.
This study used optical coherence tomography scanning and 3D reconstruction of the macular region in high myopia to examine more thoroughly and carefully the differences between high myopia-related macular complications with and without dome-shape macula (DSM) and to determine whether the DSM's fine structure has an effect on them.
Retrospective analysis of the medical records of 345 eyes with high myopia who underwent an optical coherence tomography (OCT) examination. They were divided into the DSM group (69 eyes) and the group without DSM (276 eyes). Macular complications between the two groups were compared. The height of the DSM and the diameter of the dome base were measured. And then the association between DSM type, protrusion height and macular problems were analyzed.
Epiretinal membrane (ERM) and extrafoveal schisis occurred more frequently in the DSM group, but the was no statistically significant difference in the frequency of foveal schisis between the two groups. The majority of eyes in the DSM categorization had a horizontal oval-shaped domain. In the DSM group, there was no evident difference in the percentage of eyes with macular complications in the groups below 150 um and above 150 um.
OCT examination-based fine macular structure analysis reveals that DSM affects various macular problems in distinct ways. DSM could increase the risk of extrafoveal schisis and ERM while decreasing the risk of foveal schisis. The height of the DSM had no obvious impact on the prevalence of macular complications.
本研究通过光学相干断层扫描(OCT)对高度近视患者的黄斑区进行 3D 重建,更全面、仔细地观察伴有和不伴有盘状黄斑(DSM)的高度近视相关黄斑病变的差异,并确定 DSM 的精细结构是否对其有影响。
回顾性分析 345 例高度近视患者的病历,这些患者均接受了 OCT 检查。将患者分为 DSM 组(69 眼)和非 DSM 组(276 眼)。比较两组患者的黄斑病变。测量 DSM 的高度和穹顶基底的直径。然后分析 DSM 类型、隆起高度与黄斑问题之间的关系。
DSM 组中出现视网膜内膜(ERM)和黄斑区外劈裂的频率更高,但两组间黄斑区劈裂的频率无统计学差异。DSM 分类中大多数眼的盘状区呈水平椭圆形。在 DSM 组中,150μm 以下和 150μm 以上的眼的黄斑病变发生率无明显差异。
基于 OCT 检查的精细黄斑结构分析表明,DSM 以不同的方式影响各种黄斑问题。DSM 可增加黄斑区外劈裂和 ERM 的风险,同时降低黄斑区劈裂的风险。DSM 的高度对黄斑病变的发生率无明显影响。