Tian Yi-Qun, Ren Xiang, Yin Yi-Sheng, Wang Jing, Li Xing, Guo Zi-Hao, Zeng Xiao-Yong
Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
China Institute of Urology of Hubei Province, Wuhan, Hubei, China.
Front Med (Lausanne). 2024 Jan 24;11:1327882. doi: 10.3389/fmed.2024.1327882. eCollection 2024.
Laparoscopic partial nephrectomy (LPN) remains the most commonly used measure for treating localized renal cell cancer (RCC) with an increasing incidence of RCC ever since the 1990s. This study aimed to identify risk factors that affect the postoperative time of drainage and total drainage volume after LPN.
The clinical data of 612 RCC patients who received LPN from January 2012 to December 2022 in our hospital, including the postoperative drainage time and total drainage volume, were retrospectively analyzed. Univariable and multivariable linear regression and correlation analyses were used to identify the correlations between 21 factors, which include gender, age, history of alcohol consumption, family history of RCC, body weight, body mass index (BMI), and operation time, postoperative drainage time, and total drainage volume.
The mean time of drainage was 3.52 ± 0.71 days (range: 2 to 8 days), with an average total drainage volume of 259.83 ± 72.64 mL (range: 50 to 620 mL). Both univariable and multivariable linear regression analyses revealed several statistically significant associations. Gender ( = 0.04), age ( = 0.008), smoking history ( < 0.001), diabetes ( = 0.032), operation time ( = 0.014), and BMI ( = 0.023) were identified as significant factors associated with the time of drainage. On the other hand, age ( = 0.008), smoking history ( < 0.001), diabetes ( = 0.006), and BMI ( = 0.016) emerged as independent risk factors influencing the total drainage volume.
The duration of postoperative drainage was found to be associated with gender, age, smoking history, diabetes, operation time, and BMI. In contrast, the total drainage volume was primarily influenced by age, smoking history, diabetes, and high BMI following LPN. For patients with these conditions, meticulous attention to hemostasis and bleeding control is crucial during the perioperative period.
自20世纪90年代以来，腹腔镜部分肾切除术（LPN）仍然是治疗局限性肾细胞癌（RCC）最常用的方法，且RCC的发病率不断上升。本研究旨在确定影响LPN术后引流时间和总引流量的危险因素。
回顾性分析2012年1月至2022年12月在我院接受LPN的612例RCC患者的临床资料，包括术后引流时间和总引流量。采用单变量和多变量线性回归及相关性分析，以确定21个因素之间的相关性，这些因素包括性别、年龄、饮酒史、RCC家族史、体重、体重指数（BMI）以及手术时间、术后引流时间和总引流量。
平均引流时间为3.52±0.71天（范围：2至8天），平均总引流量为259.83±72.64毫升（范围：50至620毫升）。单变量和多变量线性回归分析均显示了一些具有统计学意义的关联。性别（=0.04）、年龄（=0.008）、吸烟史（<0.001）、糖尿病（=0.032）、手术时间（=0.014）和BMI（=0.023）被确定为与引流时间相关的显著因素。另一方面，年龄（=0.008）、吸烟史（<0.001）、糖尿病（=0.006）和BMI（=0.016）成为影响总引流量的独立危险因素。
发现术后引流持续时间与性别、年龄、吸烟史、糖尿病、手术时间和BMI有关。相比之下，LPN术后总引流量主要受年龄、吸烟史、糖尿病和高BMI的影响。对于患有这些疾病的患者，围手术期仔细关注止血和出血控制至关重要。
