Sawicki Caroline M, Janal Malvin N, Gonzalez Sung Hye, Wu Angie K, Schmidt Brian L, Albertson Donna G
Department of Pediatric Dentistry, New York University College of Dentistry, New York, NY, USA.
Department of Epidemiology & Health Promotion New York University College of Dentistry, New York, NY, USA.
J Pain Res. 2024 Feb 2;17:501-508. doi: 10.2147/JPR.S423318. eCollection 2024.
Oral cancer patients suffer pain at the site of the cancer, which degrades quality of life (QoL). The University of California San Francisco Oral Cancer Pain Questionnaire (UCSFOCPQ), the only validated instrument specifically designed for measuring oral cancer pain, measures the intensity and nature of pain and the level of functional restriction due to pain.
The aim of this study was to compare pain reported by untreated oral cancer patients on the UCSFOCPQ with pain they reported on the Brief Pain Inventory (BPI), an instrument widely used to evaluate cancer and non-cancer pain.
The correlation between pain measured by the two instruments and clinical characteristics were analyzed. Thirty newly diagnosed oral cancer patients completed the UCSFOCPQ and the BPI.
Pain severity measurements made by the UCSFOCPQ and BPI were concordant; however, the widely used BPI average pain over 24 hours score appeared less sensitive to detect association of oral cancer pain with clinical characteristics of patients prior to treatment (nodal status, depth of invasion, DOI). A BPI average score that includes responses to questions that measure both pain severity and interference with function performs similarly to the UCSFOCPQ in detection of associations with nodal status, pathologic T stage (pT stage), stage and depth of invasion (DOI).
Pain assessment instruments that measure sensory and interference dimensions of oral cancer pain correlate with biologic features and clinical behavior.
口腔癌患者会在癌症部位遭受疼痛，这会降低生活质量（QoL）。加利福尼亚大学旧金山分校口腔癌疼痛问卷（UCSFOCPQ）是唯一经过验证的专门用于测量口腔癌疼痛的工具，可测量疼痛的强度和性质以及因疼痛导致的功能受限程度。
本研究的目的是比较未经治疗的口腔癌患者在UCSFOCPQ上报告的疼痛与他们在简明疼痛量表（BPI）上报告的疼痛，BPI是一种广泛用于评估癌症和非癌症疼痛的工具。
分析了两种工具测量的疼痛与临床特征之间的相关性。30名新诊断的口腔癌患者完成了UCSFOCPQ和BPI。
UCSFOCPQ和BPI进行的疼痛严重程度测量结果一致；然而，广泛使用的BPI 24小时平均疼痛评分在检测口腔癌疼痛与治疗前患者临床特征（淋巴结状态、浸润深度，DOI）的关联方面似乎不太敏感。包含对测量疼痛严重程度和功能干扰问题的回答的BPI平均评分在检测与淋巴结状态、病理T分期（pT分期）、分期和浸润深度（DOI）的关联方面与UCSFOCPQ表现相似。
测量口腔癌疼痛的感觉和干扰维度的疼痛评估工具与生物学特征和临床行为相关。
