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毛细血管间距不均一性以及氧消耗与血流不匹配对心肌氧合的影响。

The effect of heterogeneity of capillary spacing and O2 consumption--blood flow mismatching on myocardial oxygenation.

作者信息

Rakusan K, Turek Z

出版信息

Adv Exp Med Biol. 1985;191:257-62. doi: 10.1007/978-1-4684-3291-6_26.

DOI:10.1007/978-1-4684-3291-6_26
PMID:3832848
Abstract

The effect of heterogeneity of capillary spacing on myocardial oxygenation was estimated for various sizes of tissue cylinder radii ranging from 8 to 18 microns, which are the values expected from the histological measurements. Similarly, the effect of mismatching between myocardial oxygen consumption and capillary blood few was analyzed. The results are summarized in charts which demonstrate that both heterogeneities are important independent tissue oxygen determinants irrespective of the mean values of these parameters. Therefore they should be included in any future evaluation of the oxygen supply to tissue.

摘要

对于半径从8到18微米不等的各种尺寸的组织圆柱体,评估了毛细血管间距异质性对心肌氧合的影响,这些数值是组织学测量所预期的。同样,分析了心肌耗氧量与毛细血管血流量不匹配的影响。结果汇总在图表中,这些图表表明,无论这些参数的平均值如何,这两种异质性都是重要的独立组织氧决定因素。因此,在未来对组织氧供应的任何评估中都应将它们包括在内。

相似文献

1
The effect of heterogeneity of capillary spacing and O2 consumption--blood flow mismatching on myocardial oxygenation.毛细血管间距不均一性以及氧消耗与血流不匹配对心肌氧合的影响。
Adv Exp Med Biol. 1985;191:257-62. doi: 10.1007/978-1-4684-3291-6_26.
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The effect of cell size and capillary spacing on myocardial oxygen supply.
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Capillary supply and utilization of intracellular oxygen in the left ventricular myocardium from rats adapted to high altitude.
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Distribution of the myocardial tissue PO2 in the rat and the inhomogeneity of the coronary bed.大鼠心肌组织氧分压的分布及冠状动脉床的不均匀性。
Pflugers Arch. 1978 Apr 25;374(1):57-66. doi: 10.1007/BF00585697.
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Capillary spacing around coronary venules suggests that diffusion distance is controlled by local tissue pO2.冠状小静脉周围的毛细血管间距表明,扩散距离受局部组织氧分压的控制。
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Myocardial capillaries and tissue oxygenation.心肌毛细血管与组织氧合
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Determinants of regional myocardial oxygen supply in the left ventricle. An experimental study in the in situ working canine heart.左心室局部心肌氧供的决定因素。在犬原位工作心脏上的实验研究。
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Computed myocardial PO2 histograms: effects of various geometrical and functional conditions.计算机心肌氧分压直方图:各种几何和功能条件的影响
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Capillary density in the isolated perfused guinea pig heart during normoxic and high-flow hypoxic perfusion.常氧灌注和高流量低氧灌注时离体灌注豚鼠心脏的毛细血管密度
Adv Exp Med Biol. 1984;180:425-32. doi: 10.1007/978-1-4684-4895-5_40.

引用本文的文献

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The coronary capillary bed and its role in blood flow and oxygen delivery: A review.冠状动脉毛细血管床及其在血流和氧输送中的作用:综述。
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Myofibre injury induces capillary disruption and regeneration of disorganized microvascular networks.肌纤维损伤会导致毛细血管破裂,并使原本有序的微血管网络再生。
J Physiol. 2022 Jan;600(1):41-60. doi: 10.1113/JP282292. Epub 2021 Dec 8.