Estroff T W, Gold M S
Adv Alcohol Subst Abuse. 1985;5(1-2):61-76. doi: 10.1300/J251v05n01_05.
Acute and chronic medical complications of cocaine abuse are dependent on cocaine's route of administration, purity and sterility. There is a predictable sequence of events which occur during cocaine withdrawal. Cocaine can cause or exacerbate psychiatric symptoms indistinguishable from a classical psychiatric disorder. IV and freebase abuse is more likely to precipitate psychiatric symptoms. Systematic medical and psychiatric evaluation in addition to detoxification allows the detection and treatment of relapse-causing conditions. This permits more intelligent treatment decisions. Possible points of pharmacological intervention are discussed and new treatments proposed.
可卡因滥用的急慢性医学并发症取决于可卡因的给药途径、纯度和无菌性。在可卡因戒断期间会出现一系列可预测的事件。可卡因可引发或加剧与典型精神疾病难以区分的精神症状。静脉注射和吸食快克更易引发精神症状。除了戒毒之外，进行系统的医学和精神评估有助于发现和治疗导致复吸的状况。这有助于做出更明智的治疗决策。文中讨论了可能的药物干预点并提出了新的治疗方法。
