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《大开眼界:一项队列研究质疑眼底检查在感染性心内膜炎诊断中的作用》。

Eyes Wide Shut: A Cohort Study Questioning the Role of Fundoscopy in Infective Endocarditis Diagnosis.

机构信息

Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Department of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

出版信息

Clin Infect Dis. 2024 Mar 20;78(3):663-666. doi: 10.1093/cid/ciae067.

DOI:10.1093/cid/ciae067
PMID:38330299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10954338/
Abstract

In this retrospective/prospective study, we assessed the role of fundoscopy in 711 episodes with suspected infective endocarditis (IE); 238 (33%) had IE. Ocular embolic events (retinal emboli or chorioretinitis/endophthalmitis) and Roth spots were found in 37 (5%) and 34 (5%) episodes, respectively, but had no impact on IE diagnosis.

摘要

在这项回顾性/前瞻性研究中,我们评估了眼底检查在 711 例疑似感染性心内膜炎(IE)患者中的作用;其中 238 例(33%)患有 IE。我们发现 37 例(5%)和 34 例(5%)患者分别出现了眼部栓塞事件(视网膜栓塞或脉络膜炎/眼内炎)和 Roth 斑,但它们对 IE 的诊断没有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/10954338/ac3823f36edc/ciae067_ga.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/10954338/ac3823f36edc/ciae067_ga.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/10954338/ac3823f36edc/ciae067_ga.jpg

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1
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Clin Infect Dis. 2024 Mar 20;78(3):663-666. doi: 10.1093/cid/ciae067.
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本文引用的文献

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Risk of embolic events before and after antibiotic treatment initiation among patients with left-side infective endocarditis.左侧感染性心内膜炎患者在开始抗生素治疗前后发生栓塞事件的风险。
Infection. 2024 Feb;52(1):117-128. doi: 10.1007/s15010-023-02066-z. Epub 2023 Jul 4.
2
Impact of nuclear imaging on diagnosis and management of infective endocarditis.核医学成像对感染性心内膜炎的诊断和治疗的影响。
Acta Cardiol. 2020 Aug;75(4):348-352. doi: 10.1080/00015385.2019.1595268. Epub 2019 Apr 13.
3
Clinical and echocardiographic predictors of embolism in infective endocarditis: systematic review and meta-analysis.
感染性心内膜炎栓塞的临床和超声心动图预测因素:系统评价和荟萃分析。
Clin Microbiol Infect. 2019 Feb;25(2):178-187. doi: 10.1016/j.cmi.2018.08.010. Epub 2018 Aug 24.
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Incidence and Risk Factors of Ocular Infection Caused by Staphylococcus aureus Bacteremia.金黄色葡萄球菌菌血症所致眼部感染的发病率及危险因素
Antimicrob Agents Chemother. 2016 Mar 25;60(4):2012-7. doi: 10.1128/AAC.02651-15. Print 2016 Apr.
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Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.《念珠菌病管理临床实践指南:美国传染病学会2016年更新版》
Clin Infect Dis. 2016 Feb 15;62(4):e1-50. doi: 10.1093/cid/civ933. Epub 2015 Dec 16.
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Infective endocarditis.感染性心内膜炎。
Lancet. 2016 Feb 27;387(10021):882-93. doi: 10.1016/S0140-6736(15)00067-7. Epub 2015 Sep 1.
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Risk factors predictive of endogenous endophthalmitis among hospitalized patients with hematogenous infections in the United States.美国血源性感染住院患者发生内源性眼内炎的预测危险因素。
Am J Ophthalmol. 2015 Mar;159(3):498-504. doi: 10.1016/j.ajo.2014.11.032. Epub 2014 Dec 6.
8
(18)F-FDG PET/CT for early detection of embolism and metastatic infection in patients with infective endocarditis.(18)F-FDG PET/CT 用于早期检测感染性心内膜炎患者的栓塞和转移性感染。
Eur J Nucl Med Mol Imaging. 2010 Jun;37(6):1189-97. doi: 10.1007/s00259-010-1380-x. Epub 2010 Mar 4.
9
Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study.21世纪感染性心内膜炎的临床表现、病因及转归:国际心内膜炎协作组前瞻性队列研究
Arch Intern Med. 2009 Mar 9;169(5):463-73. doi: 10.1001/archinternmed.2008.603.