Tachikawa Yoshihiko, Maki Yasunori, Ikeda Kento, Yoshikai Hikaru, Toyonari Nobuyuki, Hamano Hiroshi, Chiwata Naoya, Suzuyama Kenji, Takahashi Yukihiko
Division of Radiological Technology, Department of Medical Technology, Karatsu Red Cross Hospital, 2430 Watada, Karatsu, Saga 847-8588, Japan.
Division of Radiological Technology, Department of Medical Technology, Karatsu Red Cross Hospital, 2430 Watada, Karatsu, Saga 847-8588, Japan.
Magn Reson Imaging. 2024 May;108:77-85. doi: 10.1016/j.mri.2024.02.001. Epub 2024 Feb 6.
To investigate the feasibility of obtaining black-blood imaging with a large FOV from the neck to the aortic arch at 3 T using a newly modified Relaxation-Enhanced Angiography without Contrast and Triggering for Black-Blood Imaging (REACT-BB).
REACT-BB provides black-blood images by adjusting the inversion time (TI) in REACT to the null point of blood. The optimal TI for REACT-BB was investigated in 10 healthy volunteers with TI varied from 200 ms to 1400 ms. Contrast ratios were calculated between muscle and three branch arteries of the aortic arch. Additionally, a comparison between REACT-BB and MPRAGE involved evaluating the depiction of high-intensity plaques in 222 patients with stroke or transient ischemic attack. Measurements included plaque-to-muscle signal intensity ratios (PMR), plaque volumes, and carotid artery stenosis rates in 60 patients with high-intensity plaques in carotid arteries.
REACT-BB with TI = 850 ms produced the black-blood image with the best contrast between blood and background tissues. REACT-BB outperformed MPRAGE in depicting high-intensity plaques in the aortic arch (55.4% vs 45.5%) and exhibited superior overall image quality in visual assessment (3.31 ± 0.70 vs 2.89 ± 0.73; p < 0.05). Although the PMR of REACT-BB was significantly lower than MPRAGE (2.227 ± 0.601 vs 2.285 ± 0.662; P < 0.05), a strong positive correlation existed between REACT-BB and MPRAGE (ρ = 0.935; P < 0.05), and all high-intensity plaques that MPRAGE detected were clearly detected by REACT-BB.
REACT-BB provides black-blood images with uniformly suppressed fat and blood signals over a large FOV from the neck to the aortic arch with comparable or better high-signal plaque depiction than MPRAGE.
使用新改良的无对比剂触发黑血成像的弛豫增强血管造影术（REACT-BB），研究在3T条件下从颈部至主动脉弓获得大视野黑血成像的可行性。
REACT-BB通过将REACT中的反转时间（TI）调整至血液的零点来提供黑血图像。在10名健康志愿者中研究REACT-BB的最佳TI，TI范围为200毫秒至1400毫秒。计算肌肉与主动脉弓三条分支动脉之间的对比率。此外，在222例中风或短暂性脑缺血发作患者中，对REACT-BB和MPRAGE进行比较，评估高强度斑块的显示情况。测量包括60例颈动脉高强度斑块患者的斑块与肌肉信号强度比（PMR）、斑块体积和颈动脉狭窄率。
TI = 850毫秒的REACT-BB产生了血液与背景组织之间对比度最佳的黑血图像。在显示主动脉弓高强度斑块方面，REACT-BB优于MPRAGE（55.4%对45.5%），并且在视觉评估中整体图像质量更佳（3.31±0.70对2.89±0.73；p < 0.05）。虽然REACT-BB的PMR显著低于MPRAGE（2.227±0.601对2.285±0.662；P < 0.05），但REACT-BB与MPRAGE之间存在强正相关（ρ = 0.935；P < 0.05），并且MPRAGE检测到的所有高强度斑块均能被REACT-BB清晰检测到。
REACT-BB可在从颈部至主动脉弓的大视野范围内提供脂肪和血液信号均被均匀抑制的黑血图像，在显示高信号斑块方面与MPRAGE相当或更佳。
