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[囊尾蚴病所致假肥大性肌病。1例报告]

[Pseudohypertrophic myopathy caused by cysticercosis. Report of a case].

作者信息

Lana-Peixoto M I, Lana-Peixoto M A, Belisário Campos G

出版信息

Arq Neuropsiquiatr. 1985 Dec;43(4):396-402. doi: 10.1590/s0004-282x1985000400010.

DOI:10.1590/s0004-282x1985000400010
PMID:3833141
Abstract

A 25 years old woman was admitted with a history of apparent hypertrophy of the calves, specially on the left, slight pain in the legs and difficulty in walking. Electromyography showed giant motor unit potentials with complete interference pattern. Biopsy of both gastrocnemii was performed revealing a cysticercus among inflammatory infiltrate and changes of the muscle fibers. Review of the literature disclosed 12 other reported cases. The age ranged from 10 to 35 years with a median of 25 years. Pseudohypertrophic myopathy due to cysticercosis has been found twice more common in males than in females. History of epilepsy and muscle pain occurs in about one half of the cases and muscle weakness in about one third of them. Usually there is simultaneous involvement of the upper and lower limb girdles. Myotonia is rare but subcutaneous nodules are frequently found. Our case is unique in the literature in which the pseudohypertrophy was confined to the legs and electromyography showed giant motor unit potentials. The pathogenesis of this condition is discussed and attention is called to the differential diagnosis with other pseudohypertrophic muscular conditions such as pseudohypertrophic muscular dystrophy, myotonia congenita, trichinosis, hypothyroidism, amyloidosis and glycogenosis of type I (Pompe's disease) in its juvenile form.

摘要

一名25岁女性因小腿明显肥大(尤其是左侧)、腿部轻微疼痛及行走困难入院。肌电图显示巨大运动单位电位及完全干扰型。对双侧腓肠肌进行活检,结果显示在炎性浸润及肌纤维改变中发现一个囊尾蚴。文献回顾发现另外12例报告病例。年龄范围为10至35岁,中位数为25岁。囊尾蚴病所致假性肥大性肌病在男性中的发现率是女性的两倍多。约一半病例有癫痫和肌肉疼痛病史,约三分之一病例有肌肉无力症状。通常上肢和下肢带同时受累。肌强直罕见,但常发现皮下结节。我们的病例在文献中很独特,其假性肥大仅限于腿部,且肌电图显示巨大运动单位电位。本文讨论了这种情况的发病机制,并提请注意与其他假性肥大性肌肉疾病的鉴别诊断,如假性肥大性肌营养不良、先天性肌强直、旋毛虫病、甲状腺功能减退、淀粉样变性及幼年型I型糖原贮积病(庞贝病)。

相似文献

1
[Pseudohypertrophic myopathy caused by cysticercosis. Report of a case].[囊尾蚴病所致假肥大性肌病。1例报告]
Arq Neuropsiquiatr. 1985 Dec;43(4):396-402. doi: 10.1590/s0004-282x1985000400010.
2
Pseudohypertrophic myopathy in cysticerosis.囊尾蚴病所致假肥大性肌病
Neurology. 1976 Mar;26(3):270-2. doi: 10.1212/wnl.26.3.270.
3
Pseudohypertrophic myopathy in cysticercosis.囊尾蚴病所致假肥大性肌病
Neurology. 1968 Aug;18(8):767-71. doi: 10.1212/wnl.18.8.767.
4
Uncommon manifestation of human cysticercosis with muscular pseudohypertrophy.人类囊尾蚴病伴肌肉假性肥大的罕见表现。
Trop Geogr Med. 1983 Mar;35(1):75-7.
5
[Muscular pseudohypertrophy due to cysticercus: a report of 3 cases (author's transl)].囊尾蚴所致肌肉假性肥大:3例报告(作者译)
Zhonghua Nei Ke Za Zhi. 1979;18(6):409-11.
6
Generalized muscular pseudohypertrophy in cysticercosis.囊尾蚴病中的全身性肌肉假性肥大。
Postgrad Med J. 1986 Apr;62(726):299-300. doi: 10.1136/pgmj.62.726.299.
7
[Case of pseudohypertrophic progressive muscular dystrophy of Becker's type].[贝克尔型假肥大性进行性肌营养不良病例]
Neurol Neurochir Pol. 1980;14(5):571-4.
8
Muscle hypertrophy and pseudohypertrophy.肌肉肥大与假性肥大。
Pract Neurol. 2017 Oct;17(5):369-379. doi: 10.1136/practneurol-2017-001695. Epub 2017 Aug 4.
9
Myopathy in acromegaly. A case study.肢端肥大症中的肌病。一项病例研究。
Pathol Res Pract. 1983 Jun;177(1):41-6. doi: 10.1016/S0344-0338(83)80042-9.
10
Muscular hypertrophy in cysticercosis (a case report).囊尾蚴病中的肌肉肥大(病例报告)
J Postgrad Med. 1974 Jul;20(3):148-52.

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Disseminated cysticercosis with a right common femoral vein thrombosis.播散性囊尾蚴病伴右侧股总静脉血栓形成。
BMJ Case Rep. 2013 Feb 6;2013:bcr2012008175. doi: 10.1136/bcr-2012-008175.
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Disseminated cysticercosis with huge muscle hypertrophy.播散性囊尾蚴病伴巨大肌肉肥大。
Indian J Dermatol. 2009;54(1):49-51. doi: 10.4103/0019-5154.48987.
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MRI and ultrasound in solitary muscular and soft tissue cysticercosis.孤立性肌肉和软组织囊尾蚴病的磁共振成像与超声检查
Skeletal Radiol. 2005 Nov;34(11):722-6. doi: 10.1007/s00256-005-0954-3. Epub 2005 Sep 16.