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2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group.2020 年哮喘管理指南重点更新:国家哮喘教育和预防计划协调委员会专家小组工作组的报告。
J Allergy Clin Immunol. 2020 Dec;146(6):1217-1270. doi: 10.1016/j.jaci.2020.10.003.
2
Adherence in childhood asthma: the elephant in the room.儿童哮喘的依从性:房间里的大象。
Arch Dis Child. 2014 Oct;99(10):949-53. doi: 10.1136/archdischild-2014-306243. Epub 2014 May 29.
3
Nonadherence in difficult asthma - facts, myths, and a time to act.重度哮喘治疗不依从性——事实、误区及行动时机
Patient Prefer Adherence. 2013 Apr 19;7:329-36. doi: 10.2147/PPA.S38208. Print 2013.
4
Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma.哮喘成年患者吸入性糖皮质激素依从性与不良预后的关系。
J Allergy Clin Immunol. 2004 Dec;114(6):1288-93. doi: 10.1016/j.jaci.2004.09.028.
5
Adherence to oral montelukast and inhaled fluticasone in children with persistent asthma.持续性哮喘患儿对口服孟鲁司特和吸入性氟替卡松的依从性。
Pharmacotherapy. 2001 Dec;21(12):1464-7. doi: 10.1592/phco.21.20.1464.34485.
6
Telephoning the patient's pharmacy to assess adherence with asthma medications by measuring refill rate for prescriptions.致电患者的药房,通过测量处方的再填充率来评估哮喘药物的依从性。
J Pediatr. 2000 Apr;136(4):532-6. doi: 10.1016/s0022-3476(00)90019-2.
7
Risk of fatal and near-fatal asthma in relation to inhaled corticosteroid use.与吸入性糖皮质激素使用相关的致命性和近乎致命性哮喘风险。
JAMA. 1992;268(24):3462-4.

从Epic电子病历中确定吸入性糖皮质激素的依从性

Determining Adherence to Inhaled Corticosteroids From the Epic Electronic Medical Record.

作者信息

Galbreath Ashley, Schentrup Anzeela, Prabhakaran Sreekala, Baker Dawn, Hardy Alicia, Hendeles Leslie

机构信息

College of Pharmacy (AG, LH, AS), University of Florida Physicians (AS), and.

University of Florida Physicians (AS), and.

出版信息

J Pediatr Pharmacol Ther. 2024;29(1):45-48. doi: 10.5863/1551-6776-29.1.45. Epub 2024 Feb 7.

DOI:10.5863/1551-6776-29.1.45
PMID:38332964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10849692/
Abstract

OBJECTIVE

Often we call the patient's pharmacy to obtain a refill history to assess inhaled corticosteroid (ICS) adherence. The purpose of this project was to determine the accuracy of refill histories for ICS (with or without long-acting beta agonist) listed in Epic's Medication Dispense History.

METHODS

We evaluated 61 patients and used data from 38 who met the following criteria: 1) under the care of the UF Pediatric Severe Asthma Clinic; 2) taking the same dose of the same ICS product for 6 months before the patient's last clinic visit; and 3) having data available from the pharmacy where the last ICS prescription was electronically sent. We called the pharmacies to obtain a verbal report of their refill record. Then, we compared the number of refills reported to the number listed in Epic's records using a Wilcoxon matched-pairs signed-ranks test.

RESULTS

Of the 293 refill dates listed in Epic, 157 were duplicates, giving a 54% error. After deleting duplicates, the mean (SD) number of refills listed in Epic was 3.6 (2.0) compared with 3.3 (2.0) in pharmacies over a period of 6 months (p < 0.0001). After removing duplicates Epic correctly reported the total number of refills for 30 of the 38 patients (78.9%). Seven of the remaining patients had more refills listed in Epic while 1 patient had more refills dispensed.

CONCLUSION

This study indicates that our version of Epic over-reports refills thus limiting assessment of adherence. In contrast, absence of refills in Epic is a clear indication of poor adherence.

摘要

目的

我们常常致电患者的药房以获取续方记录,从而评估吸入性糖皮质激素(ICS)的依从性。本项目的目的是确定Epic系统药物配药历史记录中列出的ICS(含或不含长效β受体激动剂)续方记录的准确性。

方法

我们评估了61名患者,并使用了38名符合以下标准患者的数据:1)由佛罗里达大学儿科重症哮喘诊所负责治疗;2)在患者最后一次门诊就诊前6个月内服用相同剂量的同一种ICS产品;3)可获取最后一份ICS处方电子发送至的药房的数据。我们致电药房以获取其续方记录的口头报告。然后,我们使用Wilcoxon配对符号秩检验比较报告的续方次数与Epic系统记录中列出的次数。

结果

在Epic系统列出的293个续方日期中,157个为重复记录,错误率达54%。删除重复记录后,Epic系统列出的续方次数平均值(标准差)为3.6(2.0),而药房在6个月期间的续方次数平均值(标准差)为3.3(2.0)(p<0.0001)。删除重复记录后,Epic系统正确报告了38名患者中30名患者(78.9%)的续方总数。其余7名患者在Epic系统中列出的续方次数更多,而1名患者实际配药的续方次数更多。

结论

本研究表明,我们使用的Epic系统版本对续方次数报告过多,从而限制了对依从性的评估。相比之下,Epic系统中无续方记录则明确表明依从性较差。