Galbreath Ashley, Schentrup Anzeela, Prabhakaran Sreekala, Baker Dawn, Hardy Alicia, Hendeles Leslie
College of Pharmacy (AG, LH, AS), University of Florida Physicians (AS), and.
University of Florida Physicians (AS), and.
J Pediatr Pharmacol Ther. 2024;29(1):45-48. doi: 10.5863/1551-6776-29.1.45. Epub 2024 Feb 7.
Often we call the patient's pharmacy to obtain a refill history to assess inhaled corticosteroid (ICS) adherence. The purpose of this project was to determine the accuracy of refill histories for ICS (with or without long-acting beta agonist) listed in Epic's Medication Dispense History.
We evaluated 61 patients and used data from 38 who met the following criteria: 1) under the care of the UF Pediatric Severe Asthma Clinic; 2) taking the same dose of the same ICS product for 6 months before the patient's last clinic visit; and 3) having data available from the pharmacy where the last ICS prescription was electronically sent. We called the pharmacies to obtain a verbal report of their refill record. Then, we compared the number of refills reported to the number listed in Epic's records using a Wilcoxon matched-pairs signed-ranks test.
Of the 293 refill dates listed in Epic, 157 were duplicates, giving a 54% error. After deleting duplicates, the mean (SD) number of refills listed in Epic was 3.6 (2.0) compared with 3.3 (2.0) in pharmacies over a period of 6 months (p < 0.0001). After removing duplicates Epic correctly reported the total number of refills for 30 of the 38 patients (78.9%). Seven of the remaining patients had more refills listed in Epic while 1 patient had more refills dispensed.
This study indicates that our version of Epic over-reports refills thus limiting assessment of adherence. In contrast, absence of refills in Epic is a clear indication of poor adherence.
我们常常致电患者的药房以获取续方记录,从而评估吸入性糖皮质激素(ICS)的依从性。本项目的目的是确定Epic系统药物配药历史记录中列出的ICS(含或不含长效β受体激动剂)续方记录的准确性。
我们评估了61名患者,并使用了38名符合以下标准患者的数据:1)由佛罗里达大学儿科重症哮喘诊所负责治疗;2)在患者最后一次门诊就诊前6个月内服用相同剂量的同一种ICS产品;3)可获取最后一份ICS处方电子发送至的药房的数据。我们致电药房以获取其续方记录的口头报告。然后,我们使用Wilcoxon配对符号秩检验比较报告的续方次数与Epic系统记录中列出的次数。
在Epic系统列出的293个续方日期中,157个为重复记录,错误率达54%。删除重复记录后,Epic系统列出的续方次数平均值(标准差)为3.6(2.0),而药房在6个月期间的续方次数平均值(标准差)为3.3(2.0)(p<0.0001)。删除重复记录后,Epic系统正确报告了38名患者中30名患者(78.9%)的续方总数。其余7名患者在Epic系统中列出的续方次数更多,而1名患者实际配药的续方次数更多。
本研究表明,我们使用的Epic系统版本对续方次数报告过多,从而限制了对依从性的评估。相比之下,Epic系统中无续方记录则明确表明依从性较差。