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右心室梗死:基于摩洛哥一个心脏病学科室的经验的流行病学、临床、血管造影特征及预后

Right ventricular infarction: epidemiological, clinical, and angiographic characteristics and the outcomes through the experience of a Moroccan cardiology department.

作者信息

Bouhaddoune Youssra, Bouchlarhem Amine, Bazid Zakaria, Ismaili Nabila, El Ouafi Noha

机构信息

Department of Cardiology, Mohammed VI University Hospital of Oujda.

Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy, Mohammed the First University of Oujda, Morocco.

出版信息

Ann Med Surg (Lond). 2023 Nov 28;86(2):660-665. doi: 10.1097/MS9.0000000000001528. eCollection 2024 Feb.

Abstract

BACKGROUND

Acute myocardial infarction (MI) is a major cause of cardiovascular mortality, which is the leading cause of death in the world. Our objective in this study was to evaluate the epidemiological, clinical, and angiographic features of right ventricular infarction (RVI), as well as its complications and its therapeutic approaches.

PATIENTS AND METHODS

It is a single-centered retrospective descriptive study conducted over a period of 2 years from November 2018 to October 2020. The authors included 82 patients with RVI hospitalized in the cardiovascular ICU during the initial phase of acute coronary syndrome with persistent ST segment elevation. Patients who were diagnosed with RVI at electrocardiogram and echocardiography were recruited.

RESULTS

The authors included 500 patients hospitalized for STEMI, 82 had MI extended to the RV, reflecting a rate of 16.4%. The mean age in our study was 64±12.3 years. Dyslipidemia, diabetes mellitus, and hypertension were the most common cardiovascular risk factors among these patients. RVI co-existed with inferior MI in 62.2 of cases and in 37.8% of anterior MI, while isolated RVI was seen in only one patient. Transthoracic echocardiography showed right ventricular (RV) systolic dysfunction in 24.39% of cases, while RV dilatation was seen in only 10.9% of patients. Therapeutic approach was based essentially on revascularization with thrombolysis and coronary angiography +/- PCI. The percentage of mortality was 2.4%.

CONCLUSION

RVI is relatively rare and is mostly related to an extension of an inferior MI. Early diagnosis, prompt treatment, and appropriate are the keys to improve prognosis, and reduce complications.

摘要

背景

急性心肌梗死(MI)是心血管疾病死亡的主要原因,而心血管疾病是全球死亡的首要原因。本研究的目的是评估右心室梗死(RVI)的流行病学、临床和血管造影特征,及其并发症和治疗方法。

患者与方法

这是一项单中心回顾性描述性研究,研究时间为2018年11月至2020年10月的2年期间。作者纳入了82例在急性冠状动脉综合征初始阶段因持续性ST段抬高而入住心血管重症监护病房的RVI患者。招募了在心电图和超声心动图检查中被诊断为RVI的患者。

结果

作者纳入了500例因ST段抬高型心肌梗死住院的患者,其中82例心肌梗死扩展至右心室,发生率为16.4%。我们研究中的患者平均年龄为64±12.3岁。血脂异常、糖尿病和高血压是这些患者中最常见的心血管危险因素。RVI与下壁心肌梗死共存的病例占62.2%,与前壁心肌梗死共存的病例占37.8%,而仅1例患者为孤立性RVI。经胸超声心动图显示,24.39%的病例存在右心室(RV)收缩功能障碍,而仅10.9%的患者出现RV扩张。治疗方法主要基于溶栓和冠状动脉造影+/-经皮冠状动脉介入治疗(PCI)进行血运重建。死亡率为2.4%。

结论

RVI相对少见,主要与下壁心肌梗死的扩展有关。早期诊断、及时治疗和恰当处理是改善预后、减少并发症的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5622/10849376/f58e5b2e81c8/ms9-86-0660-g001.jpg

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