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复杂性创伤后应激障碍对双相情感障碍患者自杀风险的影响:一项横断面研究。

The Impact of Complex PTSD on Suicide Risk in Patients with Bipolar Disorder: A Cross-Sectional Study.

作者信息

Iazzolino Anna Maria, Valenza Marta, D'Angelo Martina, Longobardi Grazia, Stefano Valeria Di, Visalli Giulia, Steardo Luca, Scuderi Caterina, Steardo Luca

机构信息

Psychiatry Unit, Department of Health Sciences, University of Catanzaro Magna Graecia, 88100 Catanzaro, Italy.

Department of Physiology and Pharmacology "Vittorio Erspamer", Sapienza University of Rome, 00185 Rome, Italy.

出版信息

J Clin Med. 2024 Jan 24;13(3):673. doi: 10.3390/jcm13030673.

Abstract

BACKGROUND

Patients with bipolar disorder (BD) are more likely than the general population to experience traumatic events, particularly during childhood, and these may predict and be a risk factor for the development of complex PTSD (cPTSD). The presence of multiple traumas plays a relevant role from a psychopathological point of view, but little is known about the effect this may have on suicide attempts in patients with BD.

METHODS

A cross-sectional study was conducted comparing socio-demographic and clinical characteristics, recruiting 344 patients diagnosed with BD I and II, screened for the presence (or absence) of cPTSD using the International Trauma Questionnaire (ITQ). Suicide attempts were assessed directly during the clinical interview and from the patient's medical record.

RESULTS

The results emerging from the study indicate that cPTSD can be considered a risk factor for suicide attempts in patients with BD. Furthermore, evidence is provided to support the idea that cPTSD is highly prevalent in patients with BD and is related to a higher psychopathological burden.

CONCLUSIONS

The results recommend an urgent and comprehensive assessment of suicidal risk in patients with comorbidity of both bipolar disorder and cPTSD. There is a crucial demand for early intervention initiatives and proactive prevention strategies to address the intricate intersection of these mental health challenges.

摘要

背景

双相情感障碍(BD)患者比普通人群更有可能经历创伤性事件,尤其是在童年时期,而这些事件可能预示着复杂性创伤后应激障碍(cPTSD)的发生并成为其风险因素。从心理病理学角度来看,多重创伤的存在起着重要作用,但对于其对BD患者自杀企图可能产生的影响知之甚少。

方法

进行了一项横断面研究,比较社会人口统计学和临床特征,招募了344名诊断为I型和II型BD的患者,使用国际创伤问卷(ITQ)筛查是否存在cPTSD。在临床访谈期间直接评估自杀企图,并查阅患者的病历。

结果

研究结果表明,cPTSD可被视为BD患者自杀企图的一个风险因素。此外,有证据支持cPTSD在BD患者中高度普遍且与更高的心理病理学负担相关这一观点。

结论

研究结果建议对双相情感障碍和cPTSD共病患者的自杀风险进行紧急和全面的评估。迫切需要早期干预举措和积极的预防策略来应对这些心理健康挑战的复杂交集。

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Complex post-traumatic stress disorder.复杂性创伤后应激障碍。
Lancet. 2022 Jul 2;400(10345):60-72. doi: 10.1016/S0140-6736(22)00821-2.

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