Blum Franziska Elisabeth, Locke Andrew R, Nathan Naveen, Katz Jeffrey, Bissing David, Minhaj Mohammed, Greenberg Steven B
Department of Internal Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USA.
Department of Anesthesiology, Critical Care, and Pain Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USA.
J Clin Med. 2024 Feb 1;13(3):861. doi: 10.3390/jcm13030861.
Residual neuromuscular block (RNMB) remains a significant safety concern for patients throughout the perioperative period and is still widely under-recognized by perioperative healthcare professionals. Current literature suggests an association between RNMB and an increased risk of postoperative pulmonary complications, a prolonged length of stay in the post anesthesia care unit (PACU), and decreased patient satisfaction. The 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade provide guidance for the use of quantitative neuromuscular monitoring coupled with neuromuscular reversal to recognize and reduce the incidence of RNMB. Using sugammadex for the reversal of neuromuscular block as well as quantitative neuromuscular monitoring to quantify the degree of neuromuscular block may significantly reduce the risk of RNMB among patients undergoing general anesthesia. Studies are forthcoming to investigate how using neuromuscular blocking agent reversal with quantitative monitoring of the neuromuscular block may further improve perioperative patient safety.
残余肌松(RNMB)在围手术期始终是患者的一个重大安全问题,并且仍未被围手术期医护人员广泛认识到。当前文献表明,RNMB与术后肺部并发症风险增加、在麻醉后护理单元(PACU)的住院时间延长以及患者满意度降低之间存在关联。2023年美国麻醉医师协会《神经肌肉阻滞监测与拮抗实践指南》为使用定量神经肌肉监测结合神经肌肉逆转以识别和降低RNMB的发生率提供了指导。使用舒更葡糖进行神经肌肉阻滞逆转以及定量神经肌肉监测以量化神经肌肉阻滞程度,可能会显著降低接受全身麻醉患者发生RNMB的风险。即将开展研究,以调查使用神经肌肉阻滞剂逆转并对神经肌肉阻滞进行定量监测如何能进一步提高围手术期患者的安全性。