Effects of Elevating Zinc Supplementation on the Health and Production Parameters of High-Producing Dairy Cows.

This study's objective was to determine the effects of increasing the dietary added zinc () on the milk production, milk somatic cell count (), and immunoglobulin and antioxidant marker concentrations in the blood of dairy cows. Twelve Holstein cows (67 ± 2.5 days in milk) were assigned randomly to (1) a diet containing Zn-methionine at 76 mg/kg of DM () or (2) CTL top-dressed with about 21 mg/kg of DM extra Zn-methionine () for 70 d. The concentrations of reduced () and oxidized () glutathione, malondialdehyde (), catalase (), superoxide dismutase (), and immunoglobulins in the blood were measured on d 0, 35, and 70. Compared to CTL, +Zn decreased the dry matter intake () throughout the trial and the milk yield () during the first phase of feeding (0-35 d). It, however, increased the milk yield during the last phase (36-70 d). The +Zn tended to have lower and greater milk protein yields than CTL during the first and last feeding phases, respectively. The +Zn tended to decrease the SCC and was associated with lower plasma GSH: GSSG and lower serum SOD concentrations relative to CTL. The +Zn did not affect the immunoglobulins, MDA, or CAT. Despite the early DMI and MY reduction, the prolonged Zn-methionine supplementation at about 100 mg/kg of DM improved the milk yield, possibly as a result of the improved udder health of dairy cows.