Moraes Mariana Carvalho de, Duarte Ivone, Nunes Rui
Department of Social Sciences and Health, Faculty of Medicine, Universidad do Porto, 4200-319 Porto, Portugal.
Healthcare (Basel). 2024 Feb 1;12(3):371. doi: 10.3390/healthcare12030371.
Is pharmacovigilance at a moment of prominence for science, and in relation to governments' responsibilities towards their nations, as the new coronavirus pandemic has surprised everyone in a negative and lethal way?
Evaluate pharmacovigilance as a resource for controlling and understanding adverse events caused by vaccines in use.
This is a narrative review of the literature. Scientific articles available in databases, government bulletins and similar bodies were used. The search was carried out using the descriptors: "Pharmacovigilance AND COVID-19 in Brazil", "Vaccine Development AND COVID-19", "Vaccination Hesitancy AND COVID-19", "Public Health Surveillance AND COVID-19". The period from May 2021 to June 2022 was covered.
The occurrence of some adverse events was observed, including cases of allergy, myocarditis and rheumatoid arthritis. It is important to highlight that these adverse events were identified as rare, occurring in a small percentage of the vaccinated population. Despite these adverse events, the benefits of vaccines proved to be essential for controlling the pandemic.
The information presented highlights the importance of pharmacovigilance to continuously monitor and evaluate the safety of vaccines, identifying any potential adverse events early. This balance between risk and benefit emphasizes the need for a careful and informed approach when making decisions about vaccination policies, prioritizing public health and population safety.
鉴于新冠疫情以一种负面且致命的方式让所有人猝不及防，药物警戒在科学领域以及政府对本国的责任方面是否正处于一个突出的时刻？
评估药物警戒作为一种资源，用于控制和理解正在使用的疫苗所引发的不良事件。
这是一篇文献综述。使用了数据库中可得的科学文章、政府公告及类似机构的资料。搜索使用的描述词为：“巴西的药物警戒与新冠疫情”、“新冠疫苗研发”、“新冠疫苗接种犹豫”、“新冠公共卫生监测”。涵盖2021年5月至2022年6月这一时间段。
观察到了一些不良事件的发生，包括过敏、心肌炎和类风湿关节炎病例。需要强调的是，这些不良事件被认定为罕见，在一小部分接种人群中出现。尽管存在这些不良事件，但疫苗的益处被证明对控制疫情至关重要。
所呈现的信息凸显了药物警戒对于持续监测和评估疫苗安全性、尽早识别任何潜在不良事件的重要性。这种风险与益处之间的平衡强调了在制定疫苗接种政策决策时，需要采取谨慎且明智的方法，将公共卫生和人群安全置于优先地位。
