Svendsen Karianne, Leithe Sigrid, Trewin-Nybråten Cassia B, Balto Aina, Nes Lise Solberg, Meland Anders, Børøsund Elin, Kiserud Cecilie E, Reinertsen Kristin Valborg, Eriksen Hege R, Gjelsvik Ylva Maria, Ursin Giske
Cancer Registry of Norway, Norwegian Institute of Public Health, 0379 Oslo, Norway.
Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0317 Oslo, Norway.
Cancers (Basel). 2024 Jan 31;16(3):602. doi: 10.3390/cancers16030602.
Little is known about how health-related quality of life (HRQoL) in breast cancer cases differed from that of controls during and after the COVID-19 pandemic. This study used data from an ongoing, nationwide HRQoL survey of 4279 newly diagnosed breast cancer cases and 2911 controls to investigate how breast cancer patients fared during different phases of the pandemic compared to controls. Responders during 2020-2022 were categorized into three COVID-19-related phases: the social restrictions phase, the high infection rate phase, and the post-pandemic phase. Across phases, breast cancer cases had significantly worse scores in most HRQoL domains compared to controls. Apart from slightly more insomnia in the high infection rate phase for both cases and controls, and better social functioning for young cases in the post-COVID-19 phase, the case-control differences in HRQoL remained consistent across phases. When the phases were assessed as one period, young women and those living with children <18 years of age fared the worst among breast cancer cases, while single women fared the worst among controls. In contrast, controls living with children <18 years of age exhibited better HRQoL than controls without children. In summary, women with breast cancer did not appear to fare differently than controls in terms of HRQoL across COVID-19 phases. However, breast cancer cases with young children fared worse in their HRQoL than other breast cancer cases.
关于在2019冠状病毒病大流行期间及之后，乳腺癌患者的健康相关生活质量（HRQoL）与对照组相比有何不同，目前所知甚少。本研究使用了一项正在进行的全国性HRQoL调查的数据，该调查涉及4279例新诊断的乳腺癌患者和2911名对照组，以调查与对照组相比，乳腺癌患者在大流行的不同阶段的情况。2020年至2022年期间的受访者被分为三个与2019冠状病毒病相关的阶段：社会限制阶段、高感染率阶段和大流行后阶段。在各个阶段，与对照组相比，乳腺癌患者在大多数HRQoL领域的得分明显更差。除了在高感染率阶段，病例组和对照组的失眠情况略有增加，以及在2019冠状病毒病后阶段年轻病例的社交功能更好之外，HRQoL方面的病例对照差异在各阶段保持一致。当将这些阶段作为一个时期进行评估时，年轻女性和有18岁以下子女的乳腺癌患者在乳腺癌病例中情况最差，而单身女性在对照组中情况最差。相比之下，有18岁以下子女的对照组的HRQoL比没有子女的对照组更好。总之，在2019冠状病毒病各阶段，乳腺癌女性在HRQoL方面似乎与对照组没有差异。然而，有年幼儿童的乳腺癌患者的HRQoL比其他乳腺癌患者更差。
