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具有乳头状核特征的非侵袭性滤泡性甲状腺肿瘤(NIFTP)中的淋巴结转移

Nodal metastasis in noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP).

作者信息

Campennì Alfredo, Torregrossa Liborio, Ruggeri Rosaria Maddalena, Ovčariček Petra Petranović, Siracusa Massimiliano, Giovanella Luca

机构信息

Unit of Nuclear Medicine, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy.

Department of Surgical, Medical, Molecular Pathology and Clinical Area, University of Pisa, Pisa, Italy.

出版信息

Endocrine. 2024 Jul;85(1):142-145. doi: 10.1007/s12020-024-03719-1. Epub 2024 Feb 10.

DOI:10.1007/s12020-024-03719-1
PMID:38340243
Abstract

The term noninvasive tumor with a follicular growth pattern and nuclear features of papillary thyroid cancer (NIFTP) is used to describe a tumor currently considered as a pre-malignant lesion for which a conservative therapeutic approach (i.e., lobectomy without radioiodine therapy) is strongly suggested. However, some patients with NIFTP and loco-regional or distant metastases have been already reported. We present an adult male patient with a final histological diagnosis of NIFTP and lymph node metastasis noted at post-therapy whole-body scintigraphy performed some days after radioiodine therapy.

摘要

术语“具有滤泡样生长模式和甲状腺乳头状癌核特征的非侵袭性肿瘤(NIFTP)”用于描述一种目前被认为是癌前病变的肿瘤,对于该肿瘤强烈建议采用保守治疗方法(即不进行放射性碘治疗的叶切除术)。然而,已有一些患有NIFTP并伴有局部区域或远处转移的患者被报道。我们报告了一名成年男性患者,其最终组织学诊断为NIFTP,并且在放射性碘治疗后几天进行的治疗后全身闪烁扫描中发现了淋巴结转移。

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