Chang Yi, Li Shoujun, Zhang Hao, Hua Zhongdong, Yang Keming, Gao Huawei
State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Paediatric Cardiovascular Institute, Beijing, China.
State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Paediatric Cardiovascular Institute, Beijing, China
Interact Cardiovasc Thorac Surg. 2016 Jul;23(1):9-13. doi: 10.1093/icvts/ivw074. Epub 2016 Mar 30.
To assess the function of the left ventricular outlet tract and neoaortic valve after arterial switch operation for patients with transposition of the great arteries and left ventricular outlet tract obstruction.
The data of 40 patients, who underwent arterial switch surgery with transposition of the great arteries with left ventricular outlet tract obstruction and a concomitant left ventricular outlet tract obstruction relieving procedure, were retrospectively analysed. Ultrasonic cardiogram and intraoperative findings, surgical methods and early and follow-up results were also summarized.
Early death occurred in one case. One patient died in follow-up stage and 3 patients were lost during follow-up. In all the 35 patients accepting follow-up, 1 patient had a reoccurring left ventricular outlet tract obstruction, 1 patient had mild neoaortic stenosis, whereas mild and moderate neoaortic regurgitation occurred in 11 and 2 patients, respectively. The median pressure gradient across the left ventricular outlet tract was 6.8 mmHg (range: 2-49 mmHg) during follow-up which was statistically significant compared with that before surgery. We defined death, reintervention and rehospitalization for cardiac reasons as a cardiac event; the survival rate of being free from cardiac event for 1 year and 5 years was 92.8 ± 0.04%, respectively.
Anatomical features and pressure gradient should be used together to evaluate the severity of obstruction, whereas the mid-term outcomes can be satisfied after arterial switch operation for the appropriate candidates.
评估大动脉转位合并左心室流出道梗阻患者动脉调转术后左心室流出道及新主动脉瓣的功能。
回顾性分析40例行大动脉转位合并左心室流出道梗阻且同期行左心室流出道梗阻解除术的动脉调转手术患者的数据。总结超声心动图及术中所见、手术方法以及早期和随访结果。
1例患者早期死亡。1例患者在随访期死亡,3例患者失访。在接受随访的35例患者中,1例患者左心室流出道再次梗阻,1例患者有轻度新主动脉瓣狭窄,而分别有11例和2例患者发生轻度和中度新主动脉瓣反流。随访期间左心室流出道的平均压力阶差为6.8 mmHg(范围:2 - 49 mmHg),与术前相比有统计学意义。我们将死亡、再次干预及因心脏原因再次住院定义为心脏事件;1年和5年无心脏事件生存率分别为92.8±0.04%。
应结合解剖特征和压力阶差评估梗阻的严重程度,而对于合适的患者,动脉调转术后中期结果令人满意。