Janković D, Bernt T, Cepulić E
Jugosl Ginekol Perinatol. 1985 May-Aug;25(3-4):61-4.
In a homogeneous group of patients with diagnosis ca cervicis uteri III B and eosinophilia the concentration of IgE in serum was studied before and during therapy with radiation. In the group of 17 patients in whom concentrations of IgE before radiation were within normal limits (mean = 40.6), after radiation they did not essentially change (mean = 37.1; t less than tgr; P greater than 0.05) and eosinophilia significantly increased at the end of therapy (t = 3.38; P less than 0.05). In the second group of 16 patients higher concentrations of IgE were found before radiation (means = 251.8) and a significant decrease after radiation (mean = 184.6; t = 2.55; P less than 0.05). Eosinophilia had increased here as well (mean = 12.88; t = 8.29; P less than 0.05). Higher concentrations of IgE and eosinophilia are probably partly due to the lack of specific T-suppressor cells for IgE but also partly due to tumour antigens.
在一组诊断为子宫颈癌III B期且伴有嗜酸性粒细胞增多症的同质患者中，研究了放疗前及放疗期间血清中IgE的浓度。在17例放疗前IgE浓度在正常范围内（均值 = 40.6）的患者组中，放疗后其浓度基本未变（均值 = 37.1；t小于临界值；P大于0.05），且嗜酸性粒细胞增多症在治疗结束时显著增加（t = 3.38；P小于0.05）。在另一组16例患者中，放疗前发现IgE浓度较高（均值 = 251.8），放疗后显著降低（均值 = 184.6；t = 2.55；P小于0.05）。此处嗜酸性粒细胞增多症也有所增加（均值 = 12.88；t = 8.29；P小于0.05）。较高的IgE浓度和嗜酸性粒细胞增多症可能部分归因于缺乏针对IgE的特异性T抑制细胞，但也部分归因于肿瘤抗原。
