Malensek B
Jugosl Ginekol Perinatol. 1985 May-Aug;25(3-4):75-9.
On the basis of two randomly selected, independent, clinically and statistically comparable groups of induced labours the influence of a spasmoanalgetic combination of Valium and Dolantin on uterine activity and indirectly on the progression of labour was studied. Each group consisted of nineteen primiparous women differing from one another only by having been or not having been administrated spasmoanalgetics. All the laboures were monitored by the direct method of internal cardiotocography. Uterine activity was manually calculated with planimetrically presented active pressure area (APA). The ratio between the calculated activity in kPa/sec and cervical dilatation in cms resulted in the resistance-gram. Quantitative statistical analysis has shown significantly lower total and average ten-minute uterine activity in the group to which spasmoanalgetics were administered and where there were no changes in the duration of dilatation. Assuming that the total uterine impulse is an indirect index of cervical resistance, it can be concluded that spasmoanalgetics reduce cervical resistance.
基于两组随机选择的、独立的、临床和统计学上具有可比性的引产病例，研究了安定和度冷丁的解痉镇痛组合对子宫活动以及间接对产程进展的影响。每组由19名初产妇组成，两组之间的唯一区别在于是否使用了解痉镇痛药。所有分娩过程均通过直接内监护胎心宫缩图法进行监测。通过平面呈现的有效压力面积（APA）手动计算子宫活动。计算出的以kPa/秒为单位的活动与以厘米为单位的宫颈扩张之间的比值得出阻力图。定量统计分析表明，在使用了解痉镇痛药且宫颈扩张持续时间无变化的组中，总的和平均十分钟的子宫活动明显较低。假设总的子宫冲动是宫颈阻力的间接指标，可以得出结论，解痉镇痛药可降低宫颈阻力。
