Xiao H P, Xu Z Y
Natl Cancer Inst Monogr. 1985 Dec;69:53-8.
A correlation study linking age-adjusted lung cancer mortality rates with indices of air pollution was conducted as a first step in the investigation of the high rate of lung cancer in Liaoning Province. Mortality rates for this cancer during 1976-78 for males and females were elevated in the large industrial cities with metallurgical processing and machinery manufacturing industries, after smoking was taken into account. However, there was little correlation between measures of total suspended particulates and lung cancer rates across the 10 major cities of the Province. Neighborhood air pollution indices correlated significantly with local commune mortality rates within the largest city, and lung cancer rates were higher near certain point sources of industrial pollution (including a copper-zinc smelter). These findings indicate that the atmospheric pollution in this northern Chinese province may contribute to lung cancer risk and that further analytic epidemiologic study in this high-risk area is warranted for evaluation of the role of outdoor and indoor air pollutants.
作为调查辽宁省肺癌高发率的第一步，开展了一项将年龄调整后的肺癌死亡率与空气污染指数相联系的相关性研究。在考虑吸烟因素后，1976 - 1978年期间，有冶金加工和机械制造产业的大型工业城市中，男性和女性的这种癌症死亡率均有所上升。然而，该省10个主要城市的总悬浮颗粒物测量值与肺癌发病率之间几乎没有相关性。在最大城市中，邻里空气污染指数与当地公社死亡率显著相关，并且在某些工业污染点源（包括一座铜锌冶炼厂）附近肺癌发病率更高。这些发现表明，中国北方这个省份的大气污染可能会增加肺癌风险，并且有必要在这个高风险地区开展进一步的分析性流行病学研究，以评估室外和室内空气污染物的作用。
