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运动联合接受与承诺疗法治疗慢性疼痛:一项随机对照试验的一年随访结果。

Exercise combined with Acceptance and Commitment Therapy for chronic pain: One-year follow-up from a randomized controlled trial.

机构信息

Department of Public Health & Primary Care, Institute of Population Health, School of Medicine, Trinity College Dublin, The University of Dublin, Dublin, Ireland.

School of Public Health, Physiotherapy & Sports Science, University College Dublin, Dublin, Ireland.

出版信息

Eur J Pain. 2024 Jul;28(6):913-928. doi: 10.1002/ejp.2229. Epub 2024 Feb 13.

Abstract

BACKGROUND

Acceptance and Commitment Therapy (ACT) is a type of Cognitive Behavioural Therapy, which has demonstrated positive outcomes in individuals with chronic pain. The purpose of this study was to compare the effect of an 8-week programme combining Exercise with Acceptance and Commitment Therapy (ExACT) with a standalone supervised exercise programme at 1-year follow-up.

METHODS

One hundred and seventy-five people with chronic pain were randomly assigned to ExACT or supervised exercise only. The primary outcome was pain interference measured with the Brief Pain Inventory-Interference Scale. Secondary and treatment process outcomes included pain severity, depression, anxiety, pain catastrophizing, pain self-efficacy, fear avoidance, pain acceptance, committed action, healthcare utilization, patient satisfaction, and global impression of change. Estimates of treatment effects at 1-year follow-up were based on intention-to-treat analyses, implemented using a linear mixed-effects model.

RESULTS

Eighty-three participants (47.4%) returned the outcome measures at 1-year follow-up. No significant difference was observed between the groups for the primary outcome, pain interference. There was a statistically significant difference between the groups, in favour of ExACT for pain catastrophizing. Within group improvements that were observed within both groups at earlier timepoints were maintained at 1-year follow-up for many of the secondary and treatment process outcomes. ExACT group participants reported higher levels of satisfaction with treatment and global perceived change.

CONCLUSIONS

The study results showed no significant difference between the two groups for the primary outcome pain interference at 1-year follow-up. Future research could investigate factors that may predict and optimize outcomes from these types of intervention for people living with chronic pain.

SIGNIFICANCE

Few previous randomized controlled trials investigating ACT for chronic pain have included long-term follow-up. This study found that Exercise combined with ACT was not superior to supervised exercise alone for reducing pain interference at 1-year follow-up. Further research is necessary to identify key processes of therapeutic change and to explore how interventions may be modified to enhance clinical outcomes for people with chronic pain.

摘要

背景

接纳与承诺疗法(ACT)是一种认知行为疗法,已在慢性疼痛患者中显示出积极的效果。本研究的目的是比较结合运动与接纳与承诺疗法(ExACT)的 8 周方案与单独的监督运动方案在 1 年随访时的效果。

方法

175 名慢性疼痛患者被随机分配到 ExACT 或仅监督运动组。主要结局是使用简短疼痛量表-干扰量表测量的疼痛干扰。次要和治疗过程结局包括疼痛严重程度、抑郁、焦虑、疼痛灾难化、疼痛自我效能、恐惧回避、疼痛接受、承诺行动、医疗保健利用、患者满意度和总体变化印象。1 年随访时的治疗效果估计基于意向治疗分析,使用线性混合效应模型实施。

结果

83 名参与者(47.4%)在 1 年随访时返回了结局测量值。两组在主要结局(疼痛干扰)上无显著差异。在疼痛灾难化方面,ExACT 组优于对照组,差异具有统计学意义。在较早的时间点观察到两组内的改善,在 1 年随访时许多次要和治疗过程结局仍得到维持。ExACT 组参与者报告治疗满意度和总体感知变化更高。

结论

本研究结果显示,两组在 1 年随访时的主要结局(疼痛干扰)无显著差异。未来的研究可以调查可能预测和优化慢性疼痛患者接受此类干预的结局的因素。

意义

很少有先前的随机对照试验研究 ACT 治疗慢性疼痛,包括长期随访。本研究发现,运动结合 ACT 并不优于单独监督运动,无法降低 1 年随访时的疼痛干扰。需要进一步研究以确定治疗变化的关键过程,并探讨如何修改干预措施以增强慢性疼痛患者的临床结局。

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