Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Am J Trop Med Hyg. 2024 Feb 13;110(3):497-500. doi: 10.4269/ajtmh.23-0596. Print 2024 Mar 6.
Rickettsial diseases cover a broad spectrum of illnesses. Scrub typhus is present worldwide, and Orientia tsutsugamushi is the causative agent of this chigger mite-borne infectious illness. Infections exhibit a range of severity, from mild illness to the more severe manifestation of multiorgan failure. We report three cases of scrub fever (55-year-old female, 63-year-old female, and 29-year-old male), all cases developed focal or pan-digital gangrene. All cases were successfully treated by administering doxycycline and additional supportive measures. Digital gangrene is uncommon in scrub typhus. Clinical suspension for early diagnosis and appropriate treatment may avoid further complications.
立克次体病涵盖了广泛的疾病谱。恙虫病分布于世界各地，而恙虫病东方体则是这种恙螨传播的传染性疾病的病原体。感染的严重程度不一，从轻症到多器官衰竭等更严重的表现都有。我们报告了三例丛林热（55 岁女性、63 岁女性和 29 岁男性），所有病例均出现局部或全指（趾）干性坏疽。所有病例均通过给予多西环素和其他支持措施成功治疗。在恙虫病中，指（趾）干性坏疽并不常见。临床暂停以进行早期诊断和适当治疗可能避免进一步的并发症。
