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评估脓毒症特定来源医嘱集对急诊科经验性抗生素选择的影响。

Evaluating the Impact of Source-specific Order Sets for Sepsis on Empiric Antibiotic Selection in the Emergency Department.

作者信息

Menendez Alvarado Lourdes R, Margulis Landayan Alice, Morell Jason, Wasielewski Anthony S, Zhang Zhenwei, Levine Richard, Gauthier Timothy P

机构信息

Pharmacy Department, West Kendall Baptist Hospital, Miami, Florida, USA.

Pharmacy Department, South Miami Hospital, Miami, Florida, USA.

出版信息

Open Forum Infect Dis. 2023 Dec 22;11(2):ofad677. doi: 10.1093/ofid/ofad677. eCollection 2024 Feb.

DOI:10.1093/ofid/ofad677
PMID:38352157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10863544/
Abstract

This retrospective cohort study found that implementing source-specific antibiotic order sets for sepsis in the emergency department increased appropriate empiric antibiotic selection from 51% to 74% ( = .01).

摘要

这项回顾性队列研究发现,在急诊科针对脓毒症实施特定来源的抗生素医嘱集,可使适当的经验性抗生素选择比例从51%提高到74%(P = 0.01)。

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本文引用的文献

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Improving Sepsis Outcomes in the Era of Pay-for-Performance and Electronic Quality Measures: A Joint IDSA/ACEP/PIDS/SHEA/SHM/SIDP Position Paper.在按绩效付费和电子质量措施时代提高脓毒症治疗效果:IDSA/ACEP/PIDS/SHEA/SHM/SIDP 联合立场文件。
Clin Infect Dis. 2024 Mar 20;78(3):505-513. doi: 10.1093/cid/ciad447.
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Risk Factors for Bloodstream Infections Due to ESBL-Producing , spp., and .产超广谱β-内酰胺酶(ESBL)的[具体菌种1]、[具体菌种2]和[具体菌种3]所致血流感染的危险因素
Pharmacy (Basel). 2023 Apr 13;11(2):74. doi: 10.3390/pharmacy11020074.
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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.拯救脓毒症运动:2021年脓毒症和脓毒性休克国际管理指南
Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2.
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Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.成人社区获得性肺炎诊断和治疗。美国胸科学会和美国传染病学会的官方临床实践指南。
Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST.
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Syndrome-specific versus prospective audit and feedback interventions for reducing use of broad-spectrum antimicrobial agents.针对特定综合征的审核与反馈干预措施与前瞻性审核与反馈干预措施比较,以减少广谱抗菌药物的使用。
Am J Infect Control. 2019 Nov;47(11):1284-1289. doi: 10.1016/j.ajic.2019.04.175. Epub 2019 Jun 18.
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Cystitis and Pyelonephritis: Diagnosis, Treatment, and Prevention.膀胱炎与肾盂肾炎:诊断、治疗及预防
Prim Care. 2019 Jun;46(2):191-202. doi: 10.1016/j.pop.2019.01.001.
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National Performance on the Medicare SEP-1 Sepsis Quality Measure.国家在 Medicare SEP-1 脓毒症质量测量上的表现。
Crit Care Med. 2019 Aug;47(8):1026-1032. doi: 10.1097/CCM.0000000000003613.
8
Impact of Electronic Physician Order-Set on Antibiotic Ordering Time in Septic Patients in the Emergency Department.电子医嘱集对急诊科脓毒症患者抗生素医嘱下达时间的影响。
Appl Clin Inform. 2018 Oct;9(4):869-874. doi: 10.1055/s-0038-1676040. Epub 2018 Dec 5.
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Consideration of Occult Infection and Sepsis Mimics in the Sick Patient Without an Apparent Infectious Source.对无明显感染源的患病患者隐匿性感染及类脓毒症的考量。
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