评估脓毒症特定来源医嘱集对急诊科经验性抗生素选择的影响。
Evaluating the Impact of Source-specific Order Sets for Sepsis on Empiric Antibiotic Selection in the Emergency Department.
作者信息
Menendez Alvarado Lourdes R, Margulis Landayan Alice, Morell Jason, Wasielewski Anthony S, Zhang Zhenwei, Levine Richard, Gauthier Timothy P
机构信息
Pharmacy Department, West Kendall Baptist Hospital, Miami, Florida, USA.
Pharmacy Department, South Miami Hospital, Miami, Florida, USA.
出版信息
Open Forum Infect Dis. 2023 Dec 22;11(2):ofad677. doi: 10.1093/ofid/ofad677. eCollection 2024 Feb.
Abstract
This retrospective cohort study found that implementing source-specific antibiotic order sets for sepsis in the emergency department increased appropriate empiric antibiotic selection from 51% to 74% ( = .01).
摘要
这项回顾性队列研究发现，在急诊科针对脓毒症实施特定来源的抗生素医嘱集，可使适当的经验性抗生素选择比例从51%提高到74%（P = 0.01）。
相似文献
1
Evaluating the Impact of Source-specific Order Sets for Sepsis on Empiric Antibiotic Selection in the Emergency Department.评估脓毒症特定来源医嘱集对急诊科经验性抗生素选择的影响。
Open Forum Infect Dis. 2023 Dec 22;11(2):ofad677. doi: 10.1093/ofid/ofad677. eCollection 2024 Feb.
2
Appropriateness of antibiotic selection for pneumonia in the emergency department: pre- and post-order set changes.急诊科肺炎抗生素选择的适宜性：医嘱前置和后置改变。
Int J Pharm Pract. 2021 Oct 18;29(5):493-498. doi: 10.1093/ijpp/riab043.
3
Impact of an emergency medicine pharmacist on empiric antibiotic prescribing for pneumonia and intra-abdominal infections.急诊药师对肺炎和腹内感染经验性抗生素治疗的影响。
Am J Emerg Med. 2019 May;37(5):839-844. doi: 10.1016/j.ajem.2018.07.052. Epub 2018 Jul 29.
4
Are Early-Onset Sepsis Evaluations and Empiric Antibiotics Mandatory for All Neonates Admitted with Respiratory Distress?对于所有因呼吸窘迫入院的新生儿，是否都必须进行早发型败血症评估并使用经验性抗生素？
Am J Perinatol. 2022 Mar;39(4):444-448. doi: 10.1055/s-0040-1717070. Epub 2020 Sep 18.
5
Impact of an Antibiotic-specific Sepsis Bundle on Appropriate and Timely Antibiotic Administration for Severe Sepsis in the Emergency Department.抗生素特异性脓毒症集束化治疗对急诊科严重脓毒症患者合理及时使用抗生素的影响
J Emerg Med. 2016 Jan;50(1):79-88.e1. doi: 10.1016/j.jemermed.2015.09.007. Epub 2015 Dec 10.
6
Improving Antibiotic Stewardship in Acute Appendicitis through Risk-Based Empiric Treatment Selection.通过基于风险的经验性治疗选择改善急性阑尾炎的抗生素管理
Surg Infect (Larchmt). 2022 Feb;23(1):61-65. doi: 10.1089/sur.2021.144. Epub 2021 Oct 7.
7
Effects of empiric antibiotic treatment based on hospital cumulative antibiograms in patients with bacteraemic sepsis: a retrospective cohort study.基于医院累积抗生素药敏谱的经验性抗生素治疗对菌血症性败血症患者的影响：一项回顾性队列研究。
Clin Microbiol Infect. 2023 Jun;29(6):765-771. doi: 10.1016/j.cmi.2023.01.004. Epub 2023 Jan 11.
8
Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use.培养证实的脓毒症中抗生素耐药病原体的流行情况以及与经验性抗生素使用不足和广谱相关的结局。
JAMA Netw Open. 2020 Apr 1;3(4):e202899. doi: 10.1001/jamanetworkopen.2020.2899.
9
Implementing a collaborative sepsis protocol on the time to antibiotics in an emergency department of a saudi hospital: quasi randomized study.在沙特一家医院的急诊科实施一项关于抗生素使用时间的协作性脓毒症治疗方案：准随机研究
Crit Care Res Pract. 2014;2014:410430. doi: 10.1155/2014/410430. Epub 2014 Apr 8.
10
Impact of antibiotic allergy labels on timely and appropriate antibiotics for sepsis in the emergency department.抗生素过敏标签对急诊科脓毒症患者及时使用恰当抗生素的影响。
JAC Antimicrob Resist. 2023 Dec 11;5(6):dlad120. doi: 10.1093/jacamr/dlad120. eCollection 2023 Dec.
引用本文的文献
1
Decreased racial disparities in sepsis mortality after an order set-driven initiative: An analysis of 8151 patients.医嘱集驱动计划实施后脓毒症死亡率的种族差异减小：对8151例患者的分析
Acad Emerg Med. 2025 Jun;32(6):598-603. doi: 10.1111/acem.15083. Epub 2025 Jan 5.
本文引用的文献
1
Improving Sepsis Outcomes in the Era of Pay-for-Performance and Electronic Quality Measures: A Joint IDSA/ACEP/PIDS/SHEA/SHM/SIDP Position Paper.在按绩效付费和电子质量措施时代提高脓毒症治疗效果：IDSA/ACEP/PIDS/SHEA/SHM/SIDP 联合立场文件。
Clin Infect Dis. 2024 Mar 20;78(3):505-513. doi: 10.1093/cid/ciad447.
2
Risk Factors for Bloodstream Infections Due to ESBL-Producing , spp., and .产超广谱β-内酰胺酶（ESBL）的[具体菌种1]、[具体菌种2]和[具体菌种3]所致血流感染的危险因素
Pharmacy (Basel). 2023 Apr 13;11(2):74. doi: 10.3390/pharmacy11020074.
3
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.拯救脓毒症运动：2021年脓毒症和脓毒性休克国际管理指南
Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2.
4
Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.成人社区获得性肺炎诊断和治疗。美国胸科学会和美国传染病学会的官方临床实践指南。
Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST.
5
Syndrome-specific versus prospective audit and feedback interventions for reducing use of broad-spectrum antimicrobial agents.针对特定综合征的审核与反馈干预措施与前瞻性审核与反馈干预措施比较，以减少广谱抗菌药物的使用。
Am J Infect Control. 2019 Nov;47(11):1284-1289. doi: 10.1016/j.ajic.2019.04.175. Epub 2019 Jun 18.
6
Cystitis and Pyelonephritis: Diagnosis, Treatment, and Prevention.膀胱炎与肾盂肾炎：诊断、治疗及预防
Prim Care. 2019 Jun;46(2):191-202. doi: 10.1016/j.pop.2019.01.001.
7
National Performance on the Medicare SEP-1 Sepsis Quality Measure.国家在 Medicare SEP-1 脓毒症质量测量上的表现。
Crit Care Med. 2019 Aug;47(8):1026-1032. doi: 10.1097/CCM.0000000000003613.
8
Impact of Electronic Physician Order-Set on Antibiotic Ordering Time in Septic Patients in the Emergency Department.电子医嘱集对急诊科脓毒症患者抗生素医嘱下达时间的影响。
Appl Clin Inform. 2018 Oct;9(4):869-874. doi: 10.1055/s-0038-1676040. Epub 2018 Dec 5.
9
Consideration of Occult Infection and Sepsis Mimics in the Sick Patient Without an Apparent Infectious Source.对无明显感染源的患病患者隐匿性感染及类脓毒症的考量。
J Emerg Med. 2019 Jan;56(1):36-45. doi: 10.1016/j.jemermed.2018.09.035. Epub 2018 Nov 2.
10
Antimicrobial Stewardship in the Emergency Department.急诊科的抗菌药物管理
Emerg Med Clin North Am. 2018 Nov;36(4):853-872. doi: 10.1016/j.emc.2018.06.012. Epub 2018 Sep 6.
Zotero 插件