Departamento de Cirugía, Hospital General Universitario Dr. Balmis, Alicante, Spain.
Departamento de Cirugía, Hospital General Universitario Dr. Balmis, Alicante, Spain.
Cir Esp (Engl Ed). 2024 Jun;102(6):307-313. doi: 10.1016/j.cireng.2024.02.001. Epub 2024 Feb 12.
Solid pseudopapillary tumors (SPT) of the pancreas are rare exocrine neoplasms of the pancreas. Correct preoperative diagnosis is not always feasible. The treatment of choice is surgical excision. These tumors have a good prognosis with a high disease-free survival rate.
To describe the clinicopathological and radiological characteristics as well as short- and long-term follow-up results of patients who have undergone SPT resection.
Multicenter retrospective observational study in patients with SPT who had undergone surgery from January 2000-January 2022. We have studied preoperative, intraoperative, and postoperative variables as well as the follow-up results (mean 28 months).
20 patients with histological diagnosis of SPT in the surgical specimen were included. 90% were women; mean age was 33.5 years (13-67); 50% were asymptomatic. CT was the most used diagnostic test (90%). The most frequent location was body-tail (60%). Preoperative biopsy was performed in 13 patients (65%), which was correct in 8 patients. Surgeries performed: 7 distal pancreatectomies, 6 pancreaticoduodenectomies, 4 central pancreatectomies, 2 enucleations, and 1 total pancreatectomy. The R0 rate was 95%. Four patients presented major postoperative complications (Clavien-Dindo > II). Mean tumor size was 81 mm. Only one patient received adjuvant chemotherapy. With a mean follow-up of 28 months, 5-year disease-free survival was 95%.
SPT are large, usually located in the body-tail of the pancreas, and more frequent in women. The R0 rate obtained in our series is very high (95%). The oncological results are excellent.
胰腺实性假乳头状瘤（SPT）是一种罕见的胰腺外分泌肿瘤。术前准确诊断并非总是可行。治疗方法首选手术切除。这些肿瘤的预后良好，无疾病生存率高。
描述接受 SPT 切除的患者的临床病理和影像学特征以及短期和长期随访结果。
对 2000 年 1 月至 2022 年 1 月期间接受手术治疗的 SPT 患者进行多中心回顾性观察研究。我们研究了术前、术中、术后变量以及（平均 28 个月）随访结果。
共纳入 20 例手术标本组织学诊断为 SPT 的患者。90%为女性；平均年龄为 33.5 岁（13-67）；50%为无症状。CT 是最常用的诊断检测方法（90%）。最常见的部位是体尾（60%）。13 例患者（65%）进行了术前活检，其中 8 例诊断正确。手术方式：7 例胰体尾切除术，6 例胰十二指肠切除术，4 例胰中段切除术，2 例肿瘤剜除术，1 例全胰切除术。R0 切除率为 95%。4 例患者出现严重术后并发症（Clavien-Dindo > II）。平均肿瘤大小为 81 mm。仅 1 例患者接受辅助化疗。平均随访 28 个月，5 年无疾病生存率为 95%。
SPT 体积较大，通常位于胰腺体尾部，多见于女性。我们的研究中 R0 切除率非常高（95%）。肿瘤学结果良好。
