在匹配的亲属和非亲属移植中使用移植后环磷酰胺联合西罗莫司或环孢素预防移植物抗宿主病：对213例连续患者的双中心分析 - Suppr

Post-transplant cyclophosphamide with Sirolimus or Cyclosporine for GvHD prophylaxis in matched related and unrelated transplantation: a two-center analysis on 213 consecutive patients.

作者信息

Piemontese Simona, Lupo Stanghellini Maria Teresa, Sora Federica, Sica Simona, Peccatori Jacopo, Marcatti Magda, Metafuni Elisabetta, Giammarco Sabrina, Greco Raffaella, Bruno Alessandro, Ciceri Fabio, Bacigalupo Andrea, Chiusolo Patrizia

机构信息

Hematology and Bone Marrow transplant Unit, San Raffaele Scientific Institute IRCCS, Milano, Italy.

Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica e Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

出版信息

Bone Marrow Transplant. 2024 May;59(5):692-694. doi: 10.1038/s41409-024-02221-6. Epub 2024 Feb 14.

DOI:10.1038/s41409-024-02221-6

PMID:38355909

Abstract

摘要

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本文引用的文献

Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis.

N Engl J Med. 2023 Jun 22;388(25):2338-2348. doi: 10.1056/NEJMoa2215943.

National Marrow Donor Program-Sponsored Multicenter, Phase II Trial of HLA-Mismatched Unrelated Donor Bone Marrow Transplantation Using Post-Transplant Cyclophosphamide.

J Clin Oncol. 2021 Jun 20;39(18):1971-1982. doi: 10.1200/JCO.20.03502. Epub 2021 Apr 27.

Outcome of haploidentical versus matched sibling donors in hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.

J Hematol Oncol. 2021 Apr 1;14(1):53. doi: 10.1186/s13045-021-01065-7.

Prophylaxis and management of graft versus host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation.

Lancet Haematol. 2020 Feb;7(2):e157-e167. doi: 10.1016/S2352-3026(19)30256-X.

Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease.

N Engl J Med. 2016 Jan 7;374(1):43-53. doi: 10.1056/NEJMoa1506002.

Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation.

Blood. 2015 Feb 19;125(8):1333-8. doi: 10.1182/blood-2014-10-609032. Epub 2015 Jan 15.

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

Leukemia. 2015 Feb;29(2):396-405. doi: 10.1038/leu.2014.180. Epub 2014 Jun 4.

Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial.

Lancet Oncol. 2009 Sep;10(9):855-64. doi: 10.1016/S1470-2045(09)70225-6. Epub 2009 Aug 18.

Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients.

Am J Transplant. 2002 May;2(5):436-42. doi: 10.1034/j.1600-6143.2002.20507.x.

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Post-transplant cyclophosphamide with Sirolimus or Cyclosporine for GvHD prophylaxis in matched related and unrelated transplantation: a two-center analysis on 213 consecutive patients.

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