Bănariu G M, Tica I, Rus M, Onuc S, Neagoe G, Tica V I
Doctoral school, "Ovidius" University of Constanta, Faculty of Medicine, Constanta, Romania.
Medical Department, "Ovidius" University of Constanta, Faculty of Medicine, Constanta, Romania.
Acta Endocrinol (Buchar). 2023 Jul-Sep;19(3):307-313. doi: 10.4183/aeb.2023.307. Epub 2024 Feb 1.
We analyzed the correlation between glycemic variability and psychological problems such as depression, anxiety disorder, and low self-esteem in pregnant and non-pregnant (excluding gestational diabetes) patients with diabetes. Besides its originality, this study might contribute to better / earlier diagnosis of these psychological conditions, with a special interest in pregnant diabetic women. Better management and cost reduction of care could be a consequence.
We compared diabetic pregnant and non-pregnant women from the perspective of the glycemic variability (for a period of 15 days prior inclusion in the study) and their results on the standardized questionnaires: Beck depression inventory, Hamilton anxiety scale - HRSA, Rosenberg self-esteem test.
A statistically significant correlation was identified in both groups between the glycemic oscillation and depression, anxiety, and low self-esteem. Diabetic pregnant women had a higher statistical significance for the correlation between the glycemic oscillation and depression, as well as between the glycemic oscillation and anxiety than non-pregnant diabetic patients. The present data justify further research. Our results could be developed into a preliminary intervention protocol, using the daily glycemic values measurements, collected by patients.
我们分析了糖尿病孕妇及非孕妇(不包括妊娠期糖尿病患者)血糖变异性与抑郁、焦虑症和自卑等心理问题之间的相关性。除了其创新性外,本研究可能有助于更好/更早地诊断这些心理状况,尤其关注糖尿病孕妇。这可能会带来更好的管理并降低护理成本。
我们从血糖变异性(纳入研究前15天期间)的角度比较了糖尿病孕妇和非孕妇,并比较了她们在标准化问卷上的结果:贝克抑郁量表、汉密尔顿焦虑量表 - HRSA、罗森伯格自尊测试。
两组中均发现血糖波动与抑郁、焦虑和自卑之间存在统计学上的显著相关性。糖尿病孕妇血糖波动与抑郁之间以及血糖波动与焦虑之间的相关性比非糖尿病孕妇具有更高的统计学意义。目前的数据证明有必要进一步研究。我们的结果可发展为一个初步的干预方案,利用患者收集的每日血糖值测量数据。