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婴儿重症监护病房:是时候做出改变了吗?

Infant Intensive Care Unit: Is it Time to Change?

作者信息

Olfat Mehrnaz, Hosseinzadeh Rayeheh, Sharifzadeh Meisam, Hassani Seyed Abbas, Goudarzi Mehrdad, Mohammadpour Masoud

机构信息

Children's Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran.

Division of Pediatric Intensive Care, Department of Pediatrics, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Indian J Pediatr. 2024 Feb 15. doi: 10.1007/s12098-024-05032-1.

DOI:10.1007/s12098-024-05032-1
PMID:38358405
Abstract

OBJECTIVES

To assess the effect of the Infant intensive care unit (InICU), a specialized unit for critically ill infants established in 2016 in authors' hospital, on infant mortality and compare the outcome with the current Pediatric intensive care units (PICU).

METHODS

In this retrospective cross-sectional study, two groups were defined; the first included expired patients aged 1 mo to 2 y admitted to PICU before the establishment of the InICU (the PICU group). The second included age-matched expired patients admitted to the InICU (the InICU group). Data were recorded using a questionnaire.

RESULTS

The authors found that the age, sex, underlying diseases, the leading cause of admission to the ICU, time of death, hospital and ICU length of stay, and the pediatric index of mortality 2 (PIM 2) score were same between the two groups. The incidence of mortality in the PICU group was 10.66 in 1000 person-month. This value was 6.37 for the InICU group (P-value <0.001). The relative risk of mortality of patients admitted to the PICU group compared to the InICU group was 1.67 (P-value <0.001).

CONCLUSIONS

Establishment of age specific InICU for infants may be beneficial in reducing infant mortality.

摘要

目的

评估作者所在医院于2016年设立的针对危重症婴儿的专科病房——婴儿重症监护病房(InICU)对婴儿死亡率的影响,并将其结果与当前的儿科重症监护病房(PICU)进行比较。

方法

在这项回顾性横断面研究中,定义了两组;第一组包括在InICU设立之前入住PICU的1个月至2岁的死亡患者(PICU组)。第二组包括年龄匹配的入住InICU的死亡患者(InICU组)。使用问卷记录数据。

结果

作者发现两组之间的年龄、性别、基础疾病、入住ICU的主要原因、死亡时间、住院和ICU住院时间以及儿科死亡率指数2(PIM 2)评分相同。PICU组的死亡率为每1000人月10.66例。InICU组的这一数值为6.37(P值<0.001)。与InICU组相比,入住PICU组患者的死亡相对风险为1.67(P值<0.001)。

结论

为婴儿设立特定年龄的InICU可能有助于降低婴儿死亡率。

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Infant Intensive Care Unit: Is it Time to Change?婴儿重症监护病房:是时候做出改变了吗?
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本文引用的文献

1
Long-term neurocognitive outcomes after pediatric intensive care: exploring the role of drug exposure.儿科重症监护后的长期神经认知结果:探讨药物暴露的作用。
Pediatr Res. 2023 Aug;94(2):603-610. doi: 10.1038/s41390-022-02460-7. Epub 2023 Jan 25.
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Causes, timing, and modes of death in a tertiary pediatric intensive care unit: Five years' experience.三级儿科重症监护病房死亡原因、时间和方式:五年经验。
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Characterization and Outcome of Two Pediatric Intensive Care Units with Different Resources.
两个资源不同的儿科重症监护病房的特征与结局
Crit Care Res Pract. 2020 Mar 17;2020:5171790. doi: 10.1155/2020/5171790. eCollection 2020.
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Comparison of Pediatric Risk of Mortality III, Pediatric Index of Mortality 2, and Pediatric Index of Mortality 3 in Predicting Mortality in a Pediatric Intensive Care Unit.小儿死亡风险评分III、小儿死亡指数2及小儿死亡指数3在预测儿科重症监护病房死亡率中的比较
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Persistence of Neuropsychological Deficits Following Pediatric Critical Illness.儿科危重症后神经认知缺陷的持续存在。
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Pediatric Index of Mortality and PIM2 scores have good calibration in a large cohort of children from a developing country.儿科死亡率指数和 PIM2 评分在发展中国家的大样本儿童中具有良好的校准度。
Biomed Res Int. 2014;2014:907871. doi: 10.1155/2014/907871. Epub 2014 Jun 15.
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Pediatric index of mortality 2 score as an outcome predictor in pediatric Intensive Care Unit in India.小儿死亡指数2评分作为印度儿科重症监护病房的预后预测指标
Indian J Crit Care Med. 2013 Sep;17(5):288-91. doi: 10.4103/0972-5229.120320.
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Clinical profile of children requiring early unplanned admission to the PICU.需要早期非计划入住儿科重症监护病房的儿童的临床特征。
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Validation of pediatric index of mortality-2 scoring system in a single pediatric intensive care unit in iran.伊朗一家儿科重症监护病房中儿童死亡率指数-2评分系统的验证
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