Nguyen G K, Neifer R
Diagn Cytopathol. 1985 Oct-Dec;1(4):327-31. doi: 10.1002/dc.2840010412.
Samples obtained by fine-needle biopsy of two benign and one malignant hemangiopericytoma revealed tumor cells with round, oval, or spindle-shaped nuclei, with variable and ill-defined filmy cytoplasm. The nuclei had a finely granular chromatin pattern with or without inconspicuous nucleoli. They were seen singly or in loose or dense cellular clusters. Focal gland-like arrangement of tumor cells was noted in some cellular clusters. Benign endothelial cells were seen among tumor cells and were not cohesive to the latter. The benign and malignant nature of hemangiopericytoma cannot be predicted by examination of the cells present in the aspirates. Also, a specific diagnosis of hemangiopericytoma could not be made on cytologic basis alone as cells of hemangiopericytoma were difficult to differentiate from those of other spindle-cell mesenchymal tumors.
通过对两例良性和一例恶性血管外皮细胞瘤进行细针穿刺活检获取的样本显示，肿瘤细胞具有圆形、椭圆形或梭形核，细胞质呈可变且边界不清的薄膜状。细胞核具有细颗粒状染色质模式，有或无不明显的核仁。它们单个出现，或呈松散或密集的细胞簇。在一些细胞簇中发现肿瘤细胞呈局灶性腺样排列。在肿瘤细胞之间可见良性内皮细胞，且与后者无黏附性。血管外皮细胞瘤的良恶性不能通过检查抽吸物中的细胞来预测。此外，仅根据细胞学基础无法对血管外皮细胞瘤做出明确诊断，因为血管外皮细胞瘤的细胞很难与其他梭形细胞间叶组织肿瘤的细胞区分开来。
