Klein R J
Drugs Exp Clin Res. 1985;11(12):861-4.
Hairless mice with established latent herpes simplex virus infections in their trigeminal ganglia were treated for different time intervals with various doses of adenosine monophosphate. The treatment did not eliminate the latent infection and the results suggest that the drug did not reduce the amount of reactivatable virus present in latently infected ganglia. It appears therefore that adenosine monophosphate exerts its antiviral effects through non-specific mechanisms.
三叉神经节已建立潜伏性单纯疱疹病毒感染的无毛小鼠，用不同剂量的单磷酸腺苷治疗不同时间间隔。治疗并未消除潜伏感染，结果表明该药物并未减少潜伏感染神经节中可再激活病毒的数量。因此，单磷酸腺苷似乎是通过非特异性机制发挥其抗病毒作用的。
