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高同型半胱氨酸血症在年轻个体中表现为中风:一例报告

Hyperhomocysteinemia Presenting as Stroke in a Young Individual: A Case Report.

作者信息

Rafay Abdul, Abdul Fatir Chaudhary, Hiba Halaila-Tul, Jamil Manahil, Talha Awan Muhammad

机构信息

Internal Medicine, Ameer-ud-din Medical College/Lahore General Hospital, Lahore, PAK.

Trauma and Orthopaedics, Our Lady's Hospital, Navan, IRL.

出版信息

Cureus. 2024 Jan 16;16(1):e52381. doi: 10.7759/cureus.52381. eCollection 2024 Jan.

Abstract

This case report details the sudden onset of an ischemic stroke in a man in his late 20s, attributed to elevated homocysteine levels. Despite his young age, the patient exhibited increased homocysteine levels, a recognized stroke risk factor. This report underscores the critical importance of recognizing hyperhomocysteinemia as a potential underlying cause of strokes, even in younger age groups. Following ischemic stroke-directed treatment along with the addition of folic acid, vitamin B6, vitamin B12, and methylcobalamin, the patient's condition improved, leading to discharge with normalized homocysteine levels. Highlighting the significance of identifying this risk factor is particularly essential in regions like Pakistan, where a notably high prevalence of hyperhomocysteinemia has been reported. This case serves as a poignant reminder of the need for comprehensive stroke evaluations, urging medical practitioners to consider homocysteine as a potential contributing factor, even when dealing with young and healthy patients.

摘要

本病例报告详细介绍了一名28岁左右男性突然发生缺血性中风,原因是同型半胱氨酸水平升高。尽管患者年轻,但同型半胱氨酸水平却有所升高,这是一个公认的中风危险因素。本报告强调了认识到高同型半胱氨酸血症作为中风潜在根本原因的至关重要性,即使在较年轻的年龄组中也是如此。在进行缺血性中风针对性治疗并补充叶酸、维生素B6、维生素B12和甲钴胺后,患者病情有所改善,出院时同型半胱氨酸水平恢复正常。在巴基斯坦等地区,报告显示高同型半胱氨酸血症患病率显著较高,因此识别这一危险因素的重要性尤为突出。本病例有力地提醒人们需要进行全面的中风评估,敦促医学从业者即使在面对年轻健康的患者时,也要将同型半胱氨酸视为潜在的促成因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ba0/10867708/70e5f8545034/cureus-0016-00000052381-i01.jpg

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