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结节病性神经病变的影像学见解

Insights into neurosarcoidosis: an imaging perspective.

作者信息

Cicilet Soumya, Reddy K Shreyas, Kancharla Meghana

机构信息

St. John's Medical College Hospital, Bengaluru, Karnataka, India.

出版信息

Pol J Radiol. 2023 Dec 15;88:e582-e588. doi: 10.5114/pjr.2023.134021. eCollection 2023.

Abstract

Neurosarcoidosis is a complex and multifaceted inflammatory disorder affecting the nervous system. The disease, characterized by non-caseating granulomas, primarily involves the central and peripheral nervous systems. Neuro-logical manifestations vary widely and can include cranial nerve palsies, meningeal involvement, parenchymal lesions, hydrocephalus, and more. Diagnosis remains challenging due to the lack of specific imaging features, necessitating a combination of clinical evaluation, cerebrospinal fluid analysis, imaging studies, and sometimes tissue biopsy. This review article underscores the importance of the identification of various imaging features to mitigate the mortality and morbidity associated with neurosarcoidosis.

摘要

神经结节病是一种影响神经系统的复杂且多方面的炎症性疾病。该疾病以非干酪样肉芽肿为特征,主要累及中枢和周围神经系统。神经学表现差异很大,可包括颅神经麻痹、脑膜受累、实质病变、脑积水等。由于缺乏特异性影像学特征,诊断仍然具有挑战性,需要结合临床评估、脑脊液分析、影像学检查,有时还需要进行组织活检。这篇综述文章强调了识别各种影像学特征对于降低与神经结节病相关的死亡率和发病率的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a616/10867949/06a97b17be76/PJR-88-52130-g001.jpg

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