Pham Nhu Hiep, Phan Canh Duy, Dang An, Tran Kiem Hao, Chau Van Ha, Nguyen Thi Kim Hoa, Nguyen Thi My Linh, Dang Thi Tam, Nguyen Linh Giang
Oncology Center, Hue Central Hospital, Hue, Vietnam.
Pediatric Center, Hue Central Hospital, Hue, Vietnam.
Case Rep Oncol. 2024 Feb 15;17(1):256-263. doi: 10.1159/000535999. eCollection 2024 Jan-Dec.
Extranodal marginal zone lymphoma (MZL) arises in a number of epithelial tissues, including the stomach, salivary gland, lung, small bowel, thyroid, ocular adnexa, skin, and elsewhere. It has also been called low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). MALT lymphoma predominantly occurs in adults and is rare in children.
We report a case of MALT lymphoma involving the stomach, which is the most common subtype, in a 12-year-old girl. Initially, the patient relapsed after antibiotic therapy but achieved successful treatment subsequently through irradiation.
eradication therapy should be given to all patients with gastric MZL, irrespective of stage. In patients who do not respond to antibiotic therapy, treatment options such as irradiation and systemic cancer therapies should be considered, depending on the disease stage.
结外边缘区淋巴瘤(MZL)起源于多种上皮组织,包括胃、唾液腺、肺、小肠、甲状腺、眼附属器、皮肤及其他部位。它也被称为黏膜相关淋巴组织(MALT)低度B细胞淋巴瘤。MALT淋巴瘤主要发生于成人,儿童罕见。
我们报告一例12岁女孩发生的胃MALT淋巴瘤,这是最常见的亚型。最初,患者在抗生素治疗后复发,但随后通过放疗成功治愈。
所有胃MZL患者均应接受根除治疗,无论分期如何。对抗生素治疗无反应的患者,应根据疾病分期考虑放疗和全身癌症治疗等治疗方案。