Violeta Filip Petruta, Cuciureanu Denisa, Sorina Diaconu Laura, Maria Vladareanu Ana, Silvia Pop Corina
"Carol Davila" University of Medicine and Pharmacy, Bucharest.
Department of Internal Medicine II and Gastroenterology, Emergency University Hospital, Bucharest.
J Med Life. 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035.
Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas.
原发性胃淋巴瘤（PGL）是一种罕见的病理类型，由于消化道症状不具特异性，很容易被误诊。从组织学上看，PGL的类型多样，从惰性的黏膜相关淋巴组织（MALT）边缘区B细胞淋巴瘤到侵袭性的弥漫性大B细胞淋巴瘤（DLBCL）。多年来，临床试验揭示了幽门螺杆菌（H. pylori）在胃MALT淋巴瘤发病机制中的重要作用。幽门螺杆菌感染是胃淋巴瘤发生起始的一个有影响力的促进因素。长期研究表明，根除治疗可使胃淋巴瘤消退。
