Santangelo F, Mondola P, Belfiore A, Falconi C, Salvatore M, Lombardi G
Ann Endocrinol (Paris). 1985;46(6):411-3.
The Authors have investigated the effects of a thymus chromatographic fraction on TSH, T3, T4 serum values in thyroidectomized and normal controls rats before and after thymus treatment. The decrease in TSH values of thyroidectomized rats points out a possible inhibitory effect which the thymus extract may have at either the level of the adenohypophysis or hypothalamus. Moreover the TSH values in the euthyroid rats after thymus treatment showed a slight decrease, this changes are much more evident in the thyroidectomized rats after thymus treatment. In fact the plasma TSH of thyroidectomized rats drops from 97.5 +/- 4 microU/ml before thymus treatment, to 76.25 +/- 10 microU/ml after thymus treatment.
作者研究了胸腺层析组分对甲状腺切除大鼠和正常对照大鼠在胸腺治疗前后血清促甲状腺激素（TSH）、三碘甲状腺原氨酸（T3）、甲状腺素（T4）值的影响。甲状腺切除大鼠TSH值的降低表明胸腺提取物可能在腺垂体或下丘脑水平具有抑制作用。此外，胸腺治疗后甲状腺功能正常大鼠的TSH值略有下降，这种变化在胸腺治疗后的甲状腺切除大鼠中更为明显。事实上，甲状腺切除大鼠的血浆TSH从胸腺治疗前的97.5±4微单位/毫升降至胸腺治疗后的76.25±10微单位/毫升。
