Department of Radiological Technology, Faculty of Health Science, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Department of Radiation Oncology, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Sci Rep. 2024 Feb 16;14(1):3917. doi: 10.1038/s41598-024-54649-x.
Reducing the amount of projection data in computed tomography (CT), specifically sparse-view CT, can reduce exposure dose; however, image artifacts can occur. We quantitatively evaluated the effects of conditional generative adversarial networks (CGAN) on image quality restoration for sparse-view CT using simulated sparse projection images and compared them with autoencoder (AE) and U-Net models. The AE, U-Net, and CGAN models were trained using pairs of artifacts and original images; 90% of patient cases were used for training and the remaining for evaluation. Restoration of CT values was evaluated using mean error (ME) and mean absolute error (MAE). The image quality was evaluated using structural image similarity (SSIM) and peak signal-to-noise ratio (PSNR). Image quality improved in all sparse projection data; however, slight deformation in tumor and spine regions was observed, with a dispersed projection of over 5°. Some hallucination regions were observed in the CGAN results. Image resolution decreased, and blurring occurred in AE and U-Net; therefore, large deviations in ME and MAE were observed in lung and air regions, and the SSIM and PSNR results were degraded. The CGAN model achieved accurate CT value restoration and improved SSIM and PSNR compared to AE and U-Net models.
减少计算机断层扫描(CT)中的投影数据量,特别是稀疏视角 CT,可以降低辐射剂量;然而,可能会出现图像伪影。我们使用模拟稀疏投影图像,定量评估条件生成对抗网络(CGAN)对稀疏视角 CT 图像质量恢复的影响,并将其与自动编码器(AE)和 U-Net 模型进行比较。AE、U-Net 和 CGAN 模型使用带有伪影的原始图像对进行训练;90%的患者病例用于训练,其余用于评估。使用平均误差(ME)和平均绝对误差(MAE)评估 CT 值的恢复情况。使用结构相似性(SSIM)和峰值信噪比(PSNR)评估图像质量。在所有稀疏投影数据中,图像质量都有所提高;然而,在肿瘤和脊柱区域观察到轻微的变形,超过 5°的投影分散。在 CGAN 结果中观察到一些幻觉区域。AE 和 U-Net 的图像分辨率降低,出现模糊;因此,在肺和空气区域观察到 ME 和 MAE 的较大偏差,SSIM 和 PSNR 的结果降低。与 AE 和 U-Net 模型相比,CGAN 模型实现了准确的 CT 值恢复,并提高了 SSIM 和 PSNR。
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