Jahnke V
Auris Nasus Larynx. 1985;12 Suppl 2:S5-9. doi: 10.1016/s0385-8146(85)80019-5.
Surgery for cancer of the tongue and floor of the mouth has become more varied and generally more conservative, influenced by advances in oncology and modern reconstructive methods. Combined therapy is favored, with postoperative irradiation and sometimes adjunctive chemotherapy, using cis-platinum. T1 carcinomas of the tongue and floor of the mouth can be treated with either wide local excision or irradiation alone, but surgery is the preferred method. T2-T4 tumors treated by resection combined with radiation therapy promise the best results. The indications and principles of the most important operative procedures are discussed: local excision; partial and total glossectomy; excision of the floor of the mouth with marginal mandibular resection; composite resection. Mandible sparing operations such as a modification of the "pull through" technique described by Stell or temporary splitting of the mandible are oncologically safe in many cases. A radical neck dissection is indicated in each carcinoma of the tongue or floor of the mouth with palpable lymph nodes. If no nodes are palpable, an elective neck dissection appears justified in view of the high frequency of clinically occult lymph node metastases. Reconstructive measures following radical tongue and floor of the mouth operations are required for regaining mobility of the remaining tongue, for reconstruction of the floor of the mouth and for replacement of the mandible. For immediate reconstruction, the most frequently used technique is the pectoralis major myocutaneous flap which has largely replaced the previously employed local and regional flaps. A significant problem remains with mandibular reconstruction.
受肿瘤学进展和现代重建方法的影响,舌癌和口底癌的手术方式变得更加多样化,总体上也更加保守。联合治疗受到青睐,术后进行放疗,有时还辅助使用顺铂进行化疗。舌癌和口底癌的T1期癌肿可采用广泛局部切除或单纯放疗进行治疗,但手术是首选方法。经切除联合放射治疗的T2 - T4期肿瘤有望取得最佳疗效。文中讨论了最重要手术操作的适应证和原则:局部切除;部分和全舌切除术;口底切除联合下颌骨边缘切除术;联合切除术。在许多情况下,诸如对Stell描述的“牵拉通过”技术进行改良或下颌骨临时劈开等保留下颌骨的手术在肿瘤学上是安全的。对于每例可触及淋巴结的舌癌或口底癌,均需进行根治性颈清扫术。如果未触及淋巴结,鉴于临床隐匿性淋巴结转移的高发生率,选择性颈清扫术似乎是合理的。舌和口底根治性手术后需要采取重建措施,以恢复剩余舌的活动度、重建口底以及替代下颌骨。对于即刻重建,最常用的技术是胸大肌肌皮瓣,它已在很大程度上取代了先前使用的局部和区域皮瓣。下颌骨重建仍然是一个重大问题。