染色体不稳定性的计算：过去、现在和未来。

The reckoning of chromosomal instability: past, present, future.

机构信息

UW Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.

McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, USA.

出版信息

Chromosome Res. 2024 Feb 17;32(1):2. doi: 10.1007/s10577-024-09746-y.

DOI:10.1007/s10577-024-09746-y

PMID:38367036

Abstract

Quantitative measures of CIN are crucial to our understanding of its role in cancer. Technological advances have changed the way CIN is quantified, offering increased accuracy and insight. Here, we review measures of CIN through its rise as a field, discuss considerations for its measurement, and look forward to future quantification of CIN.

摘要

定量评估 CIN 对于我们理解其在癌症中的作用至关重要。技术进步改变了 CIN 的定量方式，提供了更高的准确性和更深入的见解。在这里，我们回顾了 CIN 作为一个领域发展的历程，讨论了其测量的注意事项，并展望了未来对 CIN 的定量评估。