McGovern Medical School, University of Texas Health Science Center, 6431 Fannin St., Houston, TX, 77030, USA.
Department of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School, 6400 Fannin St. #2700, Houston, TX, 77030, USA.
Int J Pediatr Otorhinolaryngol. 2024 Mar;178:111897. doi: 10.1016/j.ijporl.2024.111897. Epub 2024 Feb 14.
To depict the novel use of steroid-eluting stents in the treatment of choanal atresia (CA) restenosis and subglottic stenosis (SGS).
A retrospective chart review of three pediatric patients, one with CA and two with SGS, treated with mometasone furoate eluting mini stents (PROPEL) was performed. Patients were evaluated for restenosis and adverse events between one to twelve months postoperatively.
Postoperatively, patient one with CA showed no signs of restenosis and required no further intervention. Patient two with SGS demonstrated an open subglottic lumen with no signs of restenosis as well as improved phonation following his planned serial procedures. Post-operatively, patient three with SGS exhibited no restenosis of the subglottic lumen, tolerated intermittent tracheostomy capping, and demonstrated improved phonation.
In this case series, we outline successful treatments for the management of CA restenosis and SGS with mometasone furoate-eluting stents. To our knowledge, this is the first reported application of this treatment in pediatric patients with CA restenosis and the second reported application in pediatric patients with SGS.
描述类固醇洗脱支架在治疗后鼻孔闭锁（CA）再狭窄和声门下狭窄（SGS）中的新应用。
对 3 名儿科患者（1 名患有 CA，2 名患有 SGS）使用糠酸莫米松洗脱迷你支架（PROPEL）进行回顾性图表分析。术后 1 至 12 个月对患者进行再狭窄和不良事件评估。
术后，CA 患者 1 无再狭窄迹象，无需进一步干预。SGS 患者 2 显示声门下腔通畅，无再狭窄迹象，且计划的连续手术治疗后发音得到改善。术后，SGS 患者 3 声门下腔无再狭窄，可间歇性气管套管封堵，且发音改善。
在本病例系列中，我们总结了糠酸莫米松洗脱支架治疗 CA 再狭窄和 SGS 的成功治疗方法。据我们所知，这是该治疗方法首次应用于 CA 再狭窄的儿科患者，也是第二次应用于 SGS 的儿科患者。
