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贲门失弛缓症相关巨大食管伴呼吸困难和咳嗽。

Achalasia-associated megaoesophagus presenting with dyspnoea and cough.

机构信息

Department of Upper Gastrointestinal Surgery, Hull University Teaching Hospitals NHS Trust, Cottingham, UK

Department of Upper Gastrointestinal Surgery, Hull University Teaching Hospitals NHS Trust, Cottingham, UK.

出版信息

BMJ Case Rep. 2024 Feb 17;17(2):e258950. doi: 10.1136/bcr-2023-258950.

Abstract

We present an unusual case of achalasia presenting with dyspnoea and persistent cough. These symptoms persisted for months, leading to the patient undergoing a chest X-ray by her general practitioner which showed right basal consolidation and a density extending along the right mediastinum. CT scan was done which revealed megaoesophagus with a diameter of 7 cm causing tracheal compression, as well as right basal consolidation, consistent with aspiration. Further history revealed 6-month history of progressive swallowing difficulty, retrosternal chest pain and shortness of breath which worsened when eating solid foods. After thorough workup, a diagnosis of idiopathic achalasia (type II) was made. She was treated with laparoscopic Heller cardiomyotomy and Dor fundoplication with significant improvement at follow-up. Dyspnoea and respiratory symptoms are unusual presenting symptoms, suggesting a need to consider achalasia in a wider range of presentations. Successful treatment of achalasia depends on timely diagnosis and intervention prior to oesophageal failure.

摘要

我们呈现了一例以呼吸困难和持续性咳嗽为表现的不典型贲门失弛缓症。这些症状持续了数月,导致患者接受了全科医生的胸部 X 光检查,显示右侧基底实变和密度沿右侧纵隔延伸。进行了 CT 扫描,显示巨食管直径为 7 厘米,导致气管受压,以及右侧基底实变,符合吸入性肺炎。进一步的病史显示,患者有 6 个月的进行性吞咽困难、胸骨后胸痛和呼吸困难的病史,进食固体食物时症状加重。经过全面检查,诊断为特发性贲门失弛缓症(II 型)。她接受了腹腔镜 Heller 肌切开术和 Dor 胃底折叠术治疗,随访时症状明显改善。呼吸困难和呼吸症状是不常见的表现症状,提示需要在更广泛的表现中考虑贲门失弛缓症。成功治疗贲门失弛缓症取决于在食管衰竭之前及时诊断和干预。

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ASGE guideline on the management of achalasia.ASGE 关于贲门失弛缓症治疗的指南。
Gastrointest Endosc. 2020 Feb;91(2):213-227.e6. doi: 10.1016/j.gie.2019.04.231. Epub 2019 Dec 13.

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