Karl Landsteiner Institute for Lung Research and Pulmonary Oncology, Vienna, Austria
Galvanize Therapeutics Inc, San Carlos, California, USA.
BMJ Case Rep. 2024 Feb 17;17(2):e256764. doi: 10.1136/bcr-2023-256764.
A man in his early 70s with a long-standing history of chronic bronchitis presented to our department 3 years ago with debilitating chronic cough and excessive sputum production. He had no previous diagnosis of chronic obstructive pulmonary disease and without evidence of severe respiratory tract infections. Due to his symptom burden and impairments in daily activities, the patient was considered to be an appropriate candidate for bronchial rheoplasty, a novel endoscopic treatment for patients with chronic bronchitis. The patient responded well to bilateral treatment but then experienced symptom recurrence roughly 14 months after completing the initial treatment. In the absence of an alternative explanation for the return of these symptoms, he then underwent uneventful retreatment. The patient, again, reported significant symptom improvement and no adverse effects since retreatment. While further studies are necessary to assess the safety and efficacy of retreatment, the findings from this case are encouraging.
一位 70 岁出头的男性，长期患有慢性支气管炎，3 年前因慢性咳嗽和过度咳痰来我院就诊。他之前没有慢性阻塞性肺疾病的诊断，也没有严重呼吸道感染的证据。由于他的症状负担和日常活动受损，患者被认为是支气管成形术的合适人选，这是一种治疗慢性支气管炎的新型内镜治疗方法。双侧治疗后，患者反应良好，但在初始治疗完成后约 14 个月时出现症状复发。由于没有其他解释这些症状复发的原因，他随后进行了顺利的再次治疗。患者再次报告说，自再次治疗以来，症状显著改善，且无不良反应。虽然还需要进一步的研究来评估再次治疗的安全性和疗效，但该病例的结果令人鼓舞。
