Epple A, Nibbio B
J Comp Physiol B. 1985;155(3):285-90. doi: 10.1007/BF00687469.
Injections of physiological and supraphysiological doses of epinephrine (E) into cardiac-cannulated eels cause a dose-related increase of plasma dopamine (DA) and norepinephrine (NE) within 3 min. Likewise, both exogenous DA and NE increase the plasma titers of the respective other two catecholamines (CAs). The baseline titers of NE and E are closely correlated. Lack of a correlation of the baseline titers of NE and E with that of DA appears to be due to a faster disappearance rate of DA from the circulation. E is strongly hyperglycemic, and the weaker glycemic action of NE may be mediated via E release. The effects of E seem to depend on a spurt-like increase rather than its titer per se. The ability of the eel to cope with very fast, excessive increases of plasma CAs raises the question of the underlying mechanisms.
向通过心脏插管的鳗鱼注射生理剂量和超生理剂量的肾上腺素（E），会在3分钟内导致血浆多巴胺（DA）和去甲肾上腺素（NE）呈剂量相关的增加。同样，外源性DA和NE都会增加另外两种儿茶酚胺（CA）的血浆水平。NE和E的基线水平密切相关。NE和E的基线水平与DA的基线水平缺乏相关性，似乎是由于DA从循环中消失的速度更快。E具有强烈的升血糖作用，而NE较弱的血糖作用可能是通过E的释放介导的。E的作用似乎取决于其类似脉冲式的增加，而非其本身的水平。鳗鱼应对血浆CA非常快速、过度增加的能力，引发了对其潜在机制的疑问。
