Stern P J, Watts H G
J Bone Joint Surg Am. 1979 Sep;61(6A):851-6.
Osteonecrosis occurred in nine of thirty-six children following renal transplantation. The distal femoral condyle was the most common location but the femoral head was the most symptomatic and required total hip replacement in three of five patients. Total steroid dosage did not correlate with the development of osteonecrosis. There were no cases of osteonecrosis in patients under the skeletal age of ten years or in patients who did not have rejection reactions. In three children non-progressive focal lesions developed, similar to those of osteochondritis dissecans.
36名儿童肾移植后有9人发生骨坏死。股骨远端髁是最常见的部位，但股骨头症状最明显，5名患者中有3人需要进行全髋关节置换。总类固醇剂量与骨坏死的发生无关。骨骼年龄在10岁以下的患者或没有排斥反应的患者中没有骨坏死病例。3名儿童出现了非进行性局灶性病变，类似于剥脱性骨软骨炎。
