Eighth Department of Acupuncture and Moxibustion.
Outpatient Department of Acupuncture and Moxibustion, Second Affiliated Hospital of Heilongjiang University of CM, Harbin 150000, China.
Zhongguo Zhen Jiu. 2024 Feb 12;44(2):123-128. doi: 10.13703/j.0255-2930.20230716-k0004.
To compare the clinical effect on acute ischemic stroke (AIS) between the combined treatment of 's abdominal acupuncture combined with the routine acupuncture and the simple routine acupuncture, and explore the influences on inflammatory factors i.e. interleukin (IL)-1β and IL-10.
Eighty patients with AIS were randomly divided into an observation group (40 cases, 1 case dropped out) and a control group (40 cases, 1 case dropped out). The routine regimens of western medicine were administered in the two groups. In addition, the routine scalp acupuncture and the body acupuncture were used in the patients of the control group. The scalp acupuncture stimulation region and acupoints included the anterior parietal-temporal oblique line, Hegu (LI 4), Chize (LU 5), Shousanli (LI 10), etc. of affected side. In the observation group, on the base of the intervention of the control group, electroacupuncture was applied to "fouth abdominal area" of 's abdominal acupuncture, with the continuous wave and the frequency of 5 Hz. In the two groups, the intervention was given twice per day, once in every morning and afternoon separately, with the needles retained for 40 min in each intervention. The interventions were delivered for 6 days a week, lasting 3 weeks. The scores of Fugl-Meyer assessment scale (FMA), Berg balance scale (BBS) and the modified Barthel index (MBI), and the levels of IL-1β and IL-10 in the serum were observed before and after treatment in the two groups; the effect and safety of interventions were compared between the two groups.
After treatment, the scores of FMA, BBS and MBI increased in comparison with those before treatment in the two groups (0.01), and these scores in the observation group were higher than those in the control group (<0.05, <0.01). After treatment, in the two groups, the levels of IL-1β in the serum were reduced in comparison with those before treatment (0.01), and the IL-1β level in the observation group was lower than that in the control group (0.05); the levels of IL-10 in the serum were elevated in comparison with those before treatment in the two groups (0.01) and the IL-10 level in the observation group was higher than that in the control group (<0.05). The total effective rate was 92.3% (36/39) in the observation group, which was superior to that in the control group (84.6% [33/39], <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (>0.05).
's abdominal acupuncture combined with the routine acupuncture can ameliorate the motor impairment, adjust the balance dysfunction and improve the activities of daily living in the patients with AIS. The therapeutic effect of this combined regimen is better than that of the routine acupuncture, which may be associated with the regulation of the inflammatory factors after cerebral infarction.
比较腹针联合常规针刺与单纯常规针刺治疗急性缺血性脑卒中（AIS）的临床疗效，并探讨其对白细胞介素（IL）-1β和 IL-10 等炎症因子的影响。
将 80 例 AIS 患者随机分为观察组（40 例，1 例脱落）和对照组（40 例，1 例脱落）。两组均给予西医常规治疗，对照组患者加用常规头皮针和体针，头皮针刺激区和穴位包括患侧前顶颞斜线、合谷（LI4）、尺泽（LU5）、手三里（LI10）等。观察组在对照组干预的基础上，采用“腹四针”电针，连续波，频率 5Hz，每日 2 次，上午和下午各一次，每次留针 40min。每周治疗 6 天，持续 3 周。观察两组治疗前后 Fugl-Meyer 评估量表（FMA）、Berg 平衡量表（BBS）和改良 Barthel 指数（MBI）评分及血清 IL-1β、IL-10 水平，比较两组疗效及安全性。
治疗后，两组 FMA、BBS 和 MBI 评分均高于治疗前（0.01），观察组高于对照组（均<0.05，<0.01）。治疗后，两组血清 IL-1β水平均低于治疗前（0.01），观察组低于对照组（0.05）；两组血清 IL-10 水平均高于治疗前（0.01），观察组高于对照组（均<0.05）。观察组总有效率为 92.3%（36/39），优于对照组的 84.6%（33/39，<0.05）。两组不良反应发生率比较差异无统计学意义（>0.05）。
腹针联合常规针刺可改善 AIS 患者的运动功能障碍，调节平衡功能，提高日常生活活动能力，其疗效优于常规针刺，可能与脑梗死后脑内炎症因子的调节有关。
