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The involvement of serotonin in major depression: nescience in disguise?

作者信息

Arnone Danilo, Wise Toby, Fitzgerald Paul B, Harmer Catherine J

机构信息

Department of Psychiatry, University of Ottawa, Ottawa, Canada.

Centre for Affective Disorders, Psychological Medicine, Institute of Psychiatry, Psychology and Neurosciences, King's College London, London, UK.

出版信息

Mol Psychiatry. 2024 Jan;29(1):200-202. doi: 10.1038/s41380-024-02459-y. Epub 2024 Feb 19.

DOI:10.1038/s41380-024-02459-y
PMID:38374356
Abstract
摘要

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Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making.血清素在大鼠和人类的灵活决策计算中具有可比作用。
Neuropsychopharmacology. 2024 Feb;49(3):600-608. doi: 10.1038/s41386-023-01762-6. Epub 2023 Nov 1.
2
Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression.单次剂量裸盖菇素治疗难治性重度抑郁症发作。
N Engl J Med. 2022 Nov 3;387(18):1637-1648. doi: 10.1056/NEJMoa2206443.
3
Serotonin modulates asymmetric learning from reward and punishment in healthy human volunteers.
血清素调节健康人类志愿者从奖惩中进行不对称学习。
Commun Biol. 2022 Aug 12;5(1):812. doi: 10.1038/s42003-022-03690-5.
4
Reinforcement Learning in Patients With Mood and Anxiety Disorders vs Control Individuals: A Systematic Review and Meta-analysis.心境和焦虑障碍患者与对照个体的强化学习：系统评价和荟萃分析。
JAMA Psychiatry. 2022 Apr 1;79(4):313-322. doi: 10.1001/jamapsychiatry.2022.0051.
5
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials.选择性发布抗抑郁药试验及其对明显疗效的影响：更新的新试验与旧试验比较和荟萃分析。
PLoS Med. 2022 Jan 19;19(1):e1003886. doi: 10.1371/journal.pmed.1003886. eCollection 2022 Jan.
6
The structure of the serotonin system: A PET imaging study.5-羟色胺系统的结构：一项正电子发射断层扫描成像研究。
Neuroimage. 2020 Jan 15;205:116240. doi: 10.1016/j.neuroimage.2019.116240. Epub 2019 Oct 7.
7
Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis.21 种抗抑郁药治疗成人重度抑郁症的急性治疗的疗效和可接受性比较：系统评价和网络荟萃分析。
Lancet. 2018 Apr 7;391(10128):1357-1366. doi: 10.1016/S0140-6736(17)32802-7. Epub 2018 Feb 21.
8
Instability of default mode network connectivity in major depression: a two-sample confirmation study.重度抑郁症中默认模式网络连接的不稳定性：一项双样本验证研究。
Transl Psychiatry. 2017 Apr 25;7(4):e1105. doi: 10.1038/tp.2017.40.
9
Beyond negative valence: 2-week administration of a serotonergic antidepressant enhances both reward and effort learning signals.超越负性效价：血清素能抗抑郁药两周的给药增强奖赏和努力学习信号。
PLoS Biol. 2017 Feb 16;15(2):e2000756. doi: 10.1371/journal.pbio.2000756. eCollection 2017 Feb.
10
Early changes in emotional processing as a marker of clinical response to SSRI treatment in depression.作为抑郁症患者对选择性5-羟色胺再摄取抑制剂（SSRI）治疗临床反应标志物的情绪加工早期变化。
Transl Psychiatry. 2016 Nov 22;6(11):e957. doi: 10.1038/tp.2016.130.